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低分子肝素治疗孕晚期产前非显性DIC36例临床分析(1)
http://www.100md.com 2008年7月22日 《中国实用医药》 2008年第18期
低分子肝素治疗孕晚期产前非显性DIC36例临床分析

     【摘要】 目的 探讨低分子肝素(LMWH)治疗孕晚期产前非显性弥漫性血管内凝血(DIC)的临床效果。方法 将血浆纤维蛋白原(FIB)>5.0 g/L并有产科并发症的72例患者随机分为2组:低分子肝素组(36例),LMWH 2 500 IU,腹壁皮下注射,1次/d,1~5 d。低分子右旋糖酐(低右)组36例,低右500 ml+复方丹参20 ml,静脉滴注,1~5 d。结果 有FIB升高伴有产科并发症的患者应用LMWH后,FIB明显降低,产后出血量明显减少,与低右组比较差异有统计学意义(P5.0 g/L were randomly divided with 36 patients in each group.The patients in LMWH group were treated with 2 500 IU LMWH subcutaneous injection in abdominal wall in every 12 h for 1-5 d.The patients in low molecular dextran group were treated with 500 ml low molecular dextran plus 20 ml danshen root,intervenous drop infusion for 1-5 d.Results The patients of LMWH treatment group with increasing of FIB,the FIB,the amount of postpartum hemorrhage,and the incidece of the DIC were significantly lower than those of low molecular weight hesparin(P5.0 g/L或/和D-二聚体>5.0 mg/L是孕产妇发生DIC的高危阈值[1] ......
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