溶栓治疗时间窗对急性心肌梗死后血管再通的影响
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【摘要】 目的 探讨溶栓治疗时间窗对急性心肌梗死后血管再通的影响。方法 回顾性分析37例AMI患者的溶栓疗效，根据发病后溶栓时间分为早期治疗组(0~6 h)和延迟治疗组(6~12 h)。结果 早期治疗(0~6 h)组血管再通率(79.17%)与延迟治疗(>6~12 h)组的61.54%相比较，差异有统计学意义(P<0.05)；两组5周病死率、反复心绞痛和反复Ⅱ度以上房室传导阻滞(AVB)相比，差异有统计学意义(P<0.01)。结论 AMI发病后6 h内溶栓治疗，血管再通效果最好，住院病死率最低，但发病时间>6~12 h的溶栓治疗仍可取得较好的效果。
【关键词】急性心肌梗死；溶栓疗法；尿激酶
Effect of Revascularization in the Time Window after Acute Myocardial Infarction Treated with Thrombolytic Therapy
HUANG Hui,TAN Meng-shan,QIN Xi-xue.Center hospital of Du Yang,Guangxi 530809,China
【Abstract】 Objective To investigate the clinical value of revascularization in the different time after acute myocardial infarction(AMI)treated with thrombolytic therapy.Methods The 37 patients were divided into 2 groups according to thrombolytic time after AMI.Results The difference in the reopen rate of blood vessel between earlier therapy(0~6 h)and delayed therapy(>6~12 h)were significant(79.17%,61.54%,P<0.05),the difference of mortality,repeating angina pectoris,Ⅱdegree atrioventricular block during 5 weeks between these two groups were highly significant(P<0.01).Conclusion Thrombolytic therapy in 6 hours after AMI has better effect but delayed therapy(>6~12 h)still has moderate effect. ......
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