老年人胃溃疡患病相关因素的对照研究(1)
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【摘要】 目的探讨老年人胃溃疡患病相关危险因素,为临床制定有效的防治措施提供依据。方法 以广州市某两家三甲医院750例老年人胃溃疡患病作为病例组,按性别、年龄、籍贯和经济情况1∶2配对选取1500名社区无消化道疾病的老人作对照组,进行病例对照研究,通过单因素分析和多因素条件Logistic回归分析筛选主要影响因素。 结果 多因素Logistic回归分析显示:老年人胃溃疡患病有6个主要危险因素和1个保护因素,他们分别是文化程度(OR=0.697)、吸烟(OR=2.231)、饮酒(OR=1.994)、服用NSAIDs(OR=2.497)、不规律饮食(OR=2.057)、家族史(OR=1.278)和心理情况(OR=2.658)。结论 文化程度、吸烟、饮酒、服用NSAIDs、饮食、家族史和心理情况是老年人胃溃疡患病的重要影响因素,应加强老人胃溃疡疾病的防治工作。
【关键词】 老年人;胃溃疡;危险因素;对照研究
Control study of the risk factors of the gastric ulcer among the elderly
LIANG Xu-dong,LI Jun.
Internal medicine.Banfu Town hospital,guangdong,zhongshan,528459,China
【Abstract】 Objective To explore the risk factors of the gastric ulcer among the elderly in order to provide evidences for prophylaxis and treatment Gastric Ulcer among the Elderly. Methods 750 elderly gastric ulcer patients and twice number of controls,matched for age.sex,native place and economic condition. Statistic analysis of single factor and multivariate factor conditional logistic regression were performed to screen the risk factors of the the gastric ulcer among the elderly.Results By using multivariate factor conditional logistic regression showed 6 main risk factors and 1 protective factor for elderly gastric ulcer. They were Education Level (OR=0.697), smoking (OR=2.231), during (OR=1.994), Taking NSAIDs (OR=2.497), Irregular diet (OR=2.057)family medical history (OR=1.278), psychological situation (OR=2.658). Conclusion Education Level, smoking, during, taking NSAIDs, family medical history, psychological situation are the most important factors for gastric ulcer among the elderly. Health promotion should be enhanced for the elderly to control gastric ulcer effectively.
【Key words】 The elderly;Gastric ulcer; Risk factor; Control study
DOI:10.3760/cma.j.issn 1673-8799.2010.11.13
作者单位:528459广东省中山市板芙镇板芙医院内科
老年人胃溃疡是老年人好发的疾病之一。老年人因多种原因致胃黏膜屏障功能减弱,动脉硬化使胃黏膜血液供应减少及服用药物人群增加,所以老年人胃溃疡有其自身的特点,也使老年人胃溃疡防治带来一定的困难[1]。为探讨老年人胃溃疡患病相关危险因素,为临床制定有效的防治措施提供依据。本文对老年人胃溃疡作病例对照研究,现报告如下。
1 对象和方法
1.1 研究对象 病例组为2008年3月至2010年2月经诊断明确的老人胃溃疡患者共750例;其中男436例,女314例,最大年龄80岁,最小年龄61岁,平均(68.76±6.12)岁;选取1500名社区无消化道疾病的老人作对照组,其中男性872人,女性328人,最大年龄81岁,最小年龄61岁,平均(68 ......
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