高血压患者并发心房纤颤和左室肥厚中利钠多肽的预测价值(1)
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[摘要]目的 探讨利钠多肽对高血压并发心房纤颤和左室肥厚的预测价值。方法 将129例高血压患者分为A组45例(并发持续性房颤)，B组38例(并发阵发性房颤)，C组46例(不伴有房颤)；使用降压药物1年后再分为D组76例(左室肥厚消退)，E组53例(左室肥厚未消退)。结果 与B、C组比较，A组年龄及Nt-ProBNP、LAD、IVST、LVMMI有显著性差异(P<0.05)；房颤的发生与以下指标呈正相关：年龄、Nt-ProBNP、LAD、LVEDD、IVST、LVPWT及LVMMI。与E组比较，D组的Nt-ProBNP、LAD、LVEDD、IVST、阵发性房颤发生率及 ACEI、ARB的使用率有显著性差异(P <0.05)。结论 高血压伴左室肥厚及左房扩大会加大房颤的发生几率，BNP的高低也对患者的左室肥厚及房颤有一定的影响，具有一定的相关性。
[关键词]高血压；利钠多肽；心房纤颤；左室肥厚
[中图分类号] R541.3 [文献标识码] B [文章编号] 1673-9701(2011)31-30-03
The Predictive Value of Natriuretic Peptide in Hypertensive Patients with Atrial Fibrillation and Left Ventricular Hypertrophy
FU Liping
Department of Cardiology，Jiande City First People's Hospital, Jiande 311600, China
[Abstract] Objective To investigate the vallue of linas peptide on predicting of hypertensive patients with atrial fibrillation and left ventricular Hypertrophy. Methods One hundred and twenty-nine patients with hypertension were divided into group A (n=45,complicated by persistent atrial fibrillation), group B(n=38,with paroxysmal atrial fibrillation), group C(n=46,not associated with AF);using antihypertensive drugs after 1 year were divided into group D(n=76,left ventricular hypertrophy regression),group E(n=53,left ventricular hypertrophy did not subside). Results Compared group B,C, age and Nt-ProBNP, LAD, IVST, LVMMI in group A had a significant difference (P<0.05); atrial fibrillation with the following indicators were relevant: age, Nt-ProBNP, LAD, LVEDD,IVST,LVPWT and LVMMI. Compared group E, Nt-ProBNP, LAD, LVEDD, IVST, paroxysmal atrial fibrillation rate and ACEI, ARB usage in group D were significantly different(P<0.05). Conclusion Hypertension with left ventricular hypertrophy and left atrial enlargement will increase the occurrence of atrial fibrillation,BNP level have a certain influence on left ventricular hypertrophy and atrial fibrillation , has a certain relevance.
[Key words] Hypertension; Linas peptide; Atrial fibrillation; Left ventricular hypertrophy
心房纤颤又称为房颤，在心律失常患者中较为常见 ......
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