陈莎莎 赵丽娟

    【摘要】 目的：探究結直肠息肉(CRP)、结直肠癌(CRC)的发生与幽门螺杆菌(Hp)感染及CRP与血脂、尿酸(UA)的关系，为预防CRP的发生及早期预防CRC提供依据。方法：选取2018年9月-2019年12月于本院行胃镜、结肠镜和Hp检查的248例患者，收集其一般临床资料、Hp、内镜及病理结果，并依据内镜及病理结果将患者分为CRP组(n=120)、CRC组(n=28)及对照组(结肠镜检查正常，n=100)。比较三组Hp感染情况;比较CRP组与对照组的血脂、UA水平;比较CRP组中息肉不同病理类型、息肉大小、数目及部位的血脂、UA水平。结果：CRP组与CRC组Hp阳性率均高于对照组(P0.05)。结论：CRP与CRC患者Hp感染率较高。CRP患者TG、TC水平升高、HDL-L水平降低，其中腺瘤性息肉患者TG水平较高。

    【关键词】 幽门螺杆菌 结直肠息肉 结直肠癌

    [Abstract] Objective： To explore the relationship between the occurrence of colorectal polyp (CRP)， colorectal cancer (CRC) and the infection of Helicobacter pylori (Hp) and the relationship between CRP and blood lipid， uric acid (UA)， so as to provide evidence for the prevention of CRP and early prevention of CRC. Method： A total of 248 patients underwent gastroscopy， colonoscopy and Hp examination in our hospital from September 2018 to December 2019 were selected. Their general clinical data， Hp， endoscopy and pathological results were collected， and the patients were divided into CRP group (n=120) ......