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《毒物学科学杂志》.2005年.第2期
 * Xenobiotics Inhibit Hepatic Uptake and Biliary Excretion of Taurocholate in Rat Hepatocytes
 * A Toxicogenomic Approach to Drug-Induced Phospholipidosis: Analysis of Its Induction Mechanism and Establishment of a Novel in Vitro Screeni
 * Stabilization of Nrf2 by tBHQ Confers Protection against Oxidative Stress-Induced Cell Death in Human Neural Stem Cells
 * Albumin, a New Biomarker of Organophosphorus Toxicant Exposure, Identified by Mass Spectrometry
 * Chaperone Proteins Involved in Troglitazone-Induced Toxicity in Human Hepatoma Cell Lines
 * Induction of Cell-Cycle Arrest by all-trans Retinoic Acid in Mouse Embryonic Palatal Mesenchymal (MEPM) Cells
 * Aryl Hydrocarbon Receptor Expression and Activity in Cerebellar Granule Neuroblasts: Implications for Development and Dioxin Neurotoxicity
 * Aluminum-Maltolate Induces Apoptosis and Necrosis in Neuro-2a Cells: Potential Role for p53 Signaling
 * Acute Respiratory Responses of the Mouse to Chlorine
 * Downregulation of Lysyl Oxidase and Upregulation of Cellular Thiols in Rat Fetal Lung Fibroblasts Treated with Cigarette Smoke Condensate
 * Early Developmental 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Exposure Decreases Chick Embryo Heart Chronotropic Response to Isoproterenol but Not
 * Methoxychlor Induces Proliferation of the Mouse Ovarian Surface Epithelium
 * 2,2',4,6,6'-Pentachlorobiphenyl-Induced Apoptosis Is Limited by Cyclooxygenase-2 Induction
 * Acute Hemorrhagic Myocardial Necrosis and Sudden Death of Rats Exposed to a Combination of Ephedrine and Caffeine
 * Toxicokinetics of BDE 47 in Female Mice: Effect of Dose, Route of Exposure, and Time
 * Deregulation of Cell Proliferation by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells Reflects Both Genotoxic and Non
 * Effects of Co-administration of Antioxidants and Arsenicals on the Rat Urinary Bladder Epithelium
 * On the Importance of Exposure Variability to the Doses of Volatile Organic Compounds
 * Development of an Oral Exposure Mouse Model to Predict Drug-Induced Hypersensitivity Reactions by Using Reporter Antigens
 * Interaction of Polycyclic Musks and UV Filters with the Estrogen Receptor (ER), Androgen Receptor (AR), and Progesterone Receptor (PR) in Re
 * Co-culture of Primary Human Mammary Fibroblasts and MCF-7 Cells as an In Vitro Breast Cancer Model
 * Toxicokinetics and Oral Bioavailability of Halogenated Acetic Acids Mixtures in Nave and GSTzeta-Depleted Rats
 * Effects of Di-(2-Ethylhexyl)-Phthalate (DEHP) and Its Metabolites on Fatty Acid Homeostasis Regulating Proteins in Rat Placental HRP-1 Troph
 * Effects of 2,2',4,4'-Tetrachlorobiphenyl on Granulocytic HL-60 Cell Function and Expression of Cyclooxygenase-2
 * Bisphenol A Accelerates Terminal Differentiation of 3T3-L1 Cells into Adipocytes through the Phosphatidylinositol 3-Kinase Pathway
 * Activation of Mitogen Activated Protein Kinases by PCB126 (3,3',4,4',5-Pentachlorobiphenyl) in HepG2 Cells
 * Mycotoxin Fumonisin B1 Alters the Cytokine Profile and Decreases the Vaccinal Antibody Titer in Pigs
 * Effects of Repeated Oral Postnatal Exposure to Chlorpyrifos on Cholinergic Neurochemistry in Developing Rats
 * Inorganic Arsenic Compounds and Methylated Metabolites Induce Morphological Transformation in Two-Stage BALB/c 3T3 Cell Assay and Inhibit Me
 * A Mechanistic Basis for the Role of Cycle Arrest in the Genetic Toxicology of the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]
 * Inhibition of Human and Rat CYP1A2 by TCDD and Dioxin-like Chemicals
 * Essential Role of Extracellular Matrix (ECM) Overlay in Establishing the Functional Integrity of Primary Neonatal Rat Sertoli Cell/Gonocyte
 * Heart Malformation Is an Early Response to TCDD in Embryonic Zebrafish
 * Neuroanatomical Targets of the Organophosphate Chlorpyrifos by c-fos Immunolabeling
 * Increased Hepatobiliary Clearance of Unconjugated Thyroxine Determines DMP 904-Induced Alterations in Thyroid Hormone Homeostasis in Rats
 * Acute Inflammatory Responses to Stachybotrys chartarum in the Lungs of Infant Rats: Time Course and Possible Mechanisms
 * Subchronic Exposure to Low Concentrations of Di-n-Butyl Phthalate Disrupts Spermatogenesis in Xenopus laevis Frogs
 * Ah Receptor-Mediated Impairment of Interrenal Steroidogenesis Involves StAR Protein and P450scc Gene Attenuation in Rainbow Trout
 * Comparative Study of the Endocrine-Disrupting Activity of Bisphenol A and 19 Related Compounds
 * Induction of Colon Tumors in C57BL/6J Mice Fed MeIQx, IQ, or PhIP Followed by Dextran Sulfate Sodium Treatment
 * Sodium Arsenite Exposure Alters Cell Migration, Focal Adhesion Localization and Decreases Tyrosine Phosphorylation of Focal Adhesion Kinase
 * Estrogen Receptor Pathway Is Involved in the Regulation of Calbindin-D9k in the Uterus of Immature Rats
 * Ribotoxic Stress Response to the Trichothecene Deoxynivalenol in the Macrophage Involves the Src Family Kinase Hck
 * Post-Transcriptional Regulation of Metallothionein Isoform 1 and 2 Expression in the Human Breast and the MCF-10A Cell Line
 * Metabonomics in Toxicology: A Review
 * Acute Cardiopulmonary Alterations Induced by Fine Particulate Matter of So Paulo, Brazil
 * Long-Term Neurotoxicity of Chlorpyrifos: Spatial Learning Impairment on Repeated Acquisition in a Water Maze
 * Identification of the Tryptophan Photoproduct 6-Formylindolo[3,2-b]carbazole, in Cell Culture Medium, as a Factor That Controls the Backgrou
 * Characterization of Chemically Induced Hepatotoxicity in Collagen Sandwiches of Rat Hepatocytes
 * CO Inhalation at Dose Corresponding to Tobacco Smoke Worsens Cardiac Remodeling after Experimental Myocardial Infarction in Rats
 * Differential Effects of Commercial Polybrominated Diphenyl Ether and Polychlorinated Biphenyl Mixtures on Intracellular Signaling in Rat Bra
 * The Effects of Early Lead Exposure on the Brains of Adult Rhesus Monkeys: A Volumetric MRI Study
 * Effects of In Utero and Lactational TCDD Exposure on Bone Development in Differentially Sensitive Rat Lines
 * Evaluation of Oral and Intravenous Route Pharmacokinetics, Plasma Protein Binding, and Uterine Tissue Dose Metrics of Bisphenol A: A Physiol
 * Diesel Exhaust Enhances Influenza Virus Infections in Respiratory Epithelial Cells
 * The Rat Ear Vein Model for Investigating In Vivo Thrombogenicity of Ultrafine Particles (UFP)
 * A Comparison of Ratio Distributions Based on the NOAEL and the Benchmark Approach for Subchronic-to-Chronic Extrapolation
 * Changes in Androgen-Mediated Reproductive Development in Male Rat Offspring Following Exposure to a Single Oral Dose of Flutamide at Differe
 * Activator Protein-1 (AP-1) DNA Binding Activity Is Induced by Hydroxyurea in Organogenesis Stage Mouse Embryos
 * Identification of a Rapid Detoxification Mechanism for Brevetoxin in Rats
 * Temporal and Dose-Dependent Hepatic Gene Expression Patterns in Mice Provide New Insights into TCDD-Mediated Hepatotoxicity
 * Miotic Tolerance to Sarin Vapor Exposure: Role of the Sympathetic and Parasympathetic Nervous Systems
 * DNA Interaction and Dual Topoisomerase I and II Inhibition Properties of the Anti-Tumor Drug Prodigiosin
 * The Glycolytic Enzyme Glyceraldehyde-3-Phosphate Dehydrogenase Works as an Arsenate Reductase in Human Red Blood Cells and Rat Liver Cytosol
 * Reduction of Arsenate to Arsenite by Human Erythrocyte Lysate and Rat Liver Cytosol – Characterization of a Glutathione- and NAD-Dependent A
 * Perinatal Exposure to the Fungicide Prochloraz Feminizes the Male Rat Offspring
 * Manganese Acts Centrally to Stimulate Luteinizing Hormone Secretion: A Potential Influence on Female Pubertal Development
 * Protein Adduct Formation as a Molecular Mechanism in Neurotoxicity
 * Di-n-Butyl Phthalate Activates Constitutive Androstane Receptor and Pregnane X Receptor and Enhances the Expression of Steroid-Metabolizing
 * The Tobacco Alkaloid Nicotine Demonstrates Genotoxicity in Human Tonsillar Tissue and Lymphocytes
 * Effects of Two Fungicides with Multiple Modes of Action on Reproductive Endocrine Function in the Fathead Minnow (Pimephales promelas)
 * Blood Acylpeptide Hydrolase Activity Is a Sensitive Marker for Exposure to Some Organophosphate Toxicants
 * Comparative Microarray Analysis of Basal Gene Expression in Mouse Hepa-1c1c7 Wild-Type and Mutant Cell Lines
 * The Effect of the Food Matrix on In Vivo Immune Responses to Purified Peanut Allergens
 * Different Types of Combination Effects for the Induction of Micronuclei in Mouse Lymphoma Cells by Binary Mixtures of the Genotoxic Agents M
 * Chronic Developmental Lead Exposure Reduces Neurogenesis in Adult Rat Hippocampus but Does Not Impair Spatial Learning
 * Neurobehavioral Effects of Chronic Dietary and Repeated High-Level Spike Exposure to Chlorpyrifos in Rats
 * Nrf2 Activation Involves an Oxidative-Stress Independent Pathway in Tetrafluoroethylcysteine-Induced Cytotoxicity
 * Gene Expression Changes Induced in the Testis by Transplacental Exposure to High and Low Doses of 17-Ethynyl Estradiol, Genistein, or Bisphe
 * In Utero and Lactational 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure: Effects on the Prostate and Its Response to Castration in Senescent C
 * Valproic Acid II: Effects on Oxidative Stress, Mitochondrial Membrane Potential, and Cytotoxicity in Glutathione-Depleted Rat Hepatocytes
 * Biphasic Lindane-Induced Oxidation of Glutathione and Inhibition of Gap Junctions in Myometrial Cells
 * Induction of Hepatic Peroxisome Proliferation by 8–2 Telomer Alcohol Feeding In Mice: Formation of Perfluorooctanoic Acid in the Liver
 * A Systems-Based Computational Model for Dose-Response Comparisons of Two Mode of Action Hypotheses for Ethanol-Induced Neurodevelopmental To
 * Gene Ontology Mapping as an Unbiased Method for Identifying Molecular Pathways and Processes Affected by Toxicant Exposure: Application to A
 * Role of HIF Signaling on Tumorigenesis in Response to Chronic Low-Dose Arsenic Administration
 * Rapid Uptake, Metabolism, and Elimination of Inhaled Sulfuryl Fluoride Fumigant by Rats
 * Altered Retinoid Metabolism in Female Long-Evans and Han/Wistar Rats following Long-Term 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Treatmen
 * Ryanodine Receptor-Mediated Rapid Increase in Intracellular Calcium Induced by 7,8-Benzo(a)Pyrene Quinone in Human and Murine Leukocytes
 * Ultrafine Carbon Black Particles Cause Early Airway Inflammation and Have Adjuvant Activity in a Mouse Allergic Airway Disease Model
 * Research Strategies for Safety Evaluation of Nanomaterials, Part I: Evaluating the Human Health Implications of Exposure to Nanoscale Materi
 * Genistein Enhancement of Respiratory Allergen Trimellitic Anhydride-induced IgE Production by Adult B6C3F1 Mice Following In Utero and Postn
 * Effects of Chronic Dietary and Repeated Acute Exposure to Chlorpyrifos on Learning and Sustained Attention in Rats
 * Validation and Development of a Predictive Paradigm for Hemotoxicology Using a Multifunctional Bioluminescence Colony-Forming Proliferation
 * In Vitro Detection of Differential and Cell-Specific Hepatobiliary Toxicity Induced by Geldanamycin and 17-Allylaminogeldanamycin Using Dog
 * Accumulation, Tissue Distribution, and Maternal Transfer of Dietary 2,3,7,8,-Tetrachlorodibenzo-p-Dioxin: Impacts on Reproductive Success of
 * Interactions of Chronic Lead Exposure and Intermittent Stress: Consequences for Brain Catecholamine Systems and Associated Behaviors and HPA
 * Induction of Fibroblast Growth Factor-9 and Interleukin-1 Gene Expression by Motorcycle Exhaust Particulate Extracts and Benzo(a)pyrene in H
 * Chronic Oral Treatment with 13-cis-Retinoic Acid (Isotretinoin) or all-trans-Retinoic Acid Does Not Alter Depression-Like Behaviors in Rats
 * Species Differences in the Induction of Hepatocellular DNA Synthesis by Diethanolamine
 * An Integrated Addition and Interaction Model for Assessing Toxicity of Chemical Mixtures
 * Comparison of TCDD and PCB CYP1A Induction Sensitivities in Fresh Hepatocytes from Human Donors, Sprague-Dawley Rats, and Rhesus Monkeys and
 * Trans, Trans-2,4-Decadienal, a Product Found in Cooking Oil Fumes, Induces Cell Proliferation and Cytokine Production Due to Reactive Oxygen
 * Tumor Necrosis Factor--Independent Downregulation of Hepatic Cholesterol 7-Hydroxylase Gene in Mice Treated with Lead Nitrate
 * Coplanar Polychlorinated Biphenyls Activate the Aryl Hydrocarbon Receptor in Developing Tissues of Two TCDD-Responsive lacZ Mouse Lines
 * Acute and Long-Lasting Cardiac Changes Following a Single Whole-Body Exposure to Sarin Vapor in Rats
 * Butylhydroquinone Protects Cells Genetically Deficient in Glutathione Biosynthesis from Arsenite-Induced Apoptosis Without Significantly Cha
 * Progress towards Development of an Amphibian-Based Thyroid Screening Assay Using Xenopus laevis. Organismal and Thyroidal Responses to the M
 * DNA Hypomethylation Induced by Drinking Water Disinfection By-Products in Mouse and Rat Kidney
 * Evaluation of Estrogenic Activities of Aquatic Herbicides and Surfactants Using an Rainbow Trout Vitellogenin Assay
 * A Unifying Concept for Assessing Toxicological Interactions: Changes i
 * Research Strategies for Safety Evaluation of Nanomaterials, Part III:
 * In Silico Methods for Evaluating Human Allergenicity to Novel Proteins
 * Role of CYP2E1 in the Epoxidation of Acrylamide to Glycidamide and For
 * Use of a Rainbow Trout Oligonucleotide Microarray to Determine Transcr
 * Tsc2 Expression Increases the Susceptibility of Renal Tumor Cells to A
 * Azoxymethane Is a Genetic Background-Dependent Colorectal Tumor Initia
 * Involvement of the Integrin-Linked Kinase Pathway in Hexachlorobenzene
 * Long-Term Effects of a Standardized Complex Mixture of Urban Dust Part
 * Detection of Thyroid System–Disrupting Chemicals Using in Vitro and in
 * Exposure to Polybrominated Diphenyl Ethers (PBDEs): Changes in Thyroid
 * Induction of Cytochrome P450 1A5 mRNA, Protein and Enzymatic Activitie
 * Formulation and Characterization of an Experimental PCB Mixture Design
 * In Vitro Cytotoxicity of Nanoparticles in Mammalian Germline Stem Cell
 * Arginase Activity Differs with Allergen in the Effector Phase of Ovalb
 * A Study of the Relationship between Cornea Permeability and Eye Irrita
 * Inhibition and Induction of Aromatase (CYP19) Activity by Brominated F
 * Behavioral and Pathological Effects in the Rat Define Two Groups of Ne
 * D-Optimal Experimental Designs to Test for Departure from Additivity i
 * Neurobiological Effects of Bisphenol A May Be Mediated by Somatostatin
 * Effect of Chronic Exposure to Aluminium on Isoform Expression and Acti
 * Methoxychlor Inhibits Brain Mitochondrial Respiration and Increases Hy
 * Low-Level Subchronic Exposure to Wood Smoke Exacerbates Inflammatory R
 * Comparative Pulmonary Toxicity Inhalation and Instillation Studies wit
 * Effect of N-Acetylcysteine on Lipopolysaccharide-Induced Intra-uterine
 * In Utero and Lactational Exposure to TCDD; Steroidogenic Outcomes Diff
 * Protective Effect of Quercetin on Aroclor 1254–Induced Oxidative Damag
 * Roles of Exercise and Pharmacokinetics in Cerivastatin-Induced Skeleta
 * Pharmacologic and Toxicologic Evaluation of C. novyi-NT Spores
 * Modulating the Endoplasmic Reticulum Stress Response with trans-4,5-Di
 * Chemical Effects in Biological Systems—Data Dictionary (CEBS-DD): A Co
 * Basal and Zinc-Induced Metallothionein in Resistance to Cadmium, Cispl
 * Effects of Subchronically Inhaled Carbon Black in Three Species. I. Re
 * Role of Organic Anion and Amino Acid Carriers in Transport of Inorgani
 * Toxicological Effects of Gestational and Lactational Exposure to a Mix
 * CORRECTION