现在位置：百拇书刊 > 药学 > 分子药理学杂志 > 2005年.第4期 《分子药理学杂志》.2005年.第4期  * Pharmacological Differences between Human and Guinea Pig Histamine H1 Receptors: Asn84 (2.61) as Key Residue within an Additional Binding Po  * Molecular Determinants of Substrate/Inhibitor Binding to the Human and Rabbit Renal Organic Cation Transporters hOCT2 and rbOCT2  * Meclofenamic Acid and Diclofenac, Novel Templates of KCNQ2/Q3 Potassium Channel Openers, Depress Cortical Neuron Activity and Exhibit Antico  * Fusion Polypeptides That Inhibit Exocytosis: Fusing Aptamer and Cell-Penetrating Peptide Technologies and Pharmacologies  * Phosphatidylinositol-4,5-bisphosphate: Actin Dynamics and the Regulation of ATP-Dependent and -Independent Secretion  * Molecular Determinants of the Agonist Binding Domain of a P2X Receptor Channel  * Extracellular Loop 3 (EL3) and EL3-Proximal Transmembrane Helix 7 of the Mammalian Type I and Type II Gonadotropin-Releasing Hormone (GnRH)  * Glycosaminoglycans and Protein Disulfide Isomerase-Mediated Reduction of HIV Env  * TRPV1b, a Functional Human Vanilloid Receptor Splice Variant  * The Natural Mutation Encoding a C Terminus-Truncated 5-Hydroxytryptamine2B Receptor Is a Gain of Proliferative Functions  * Src Family Kinase Inhibitors Block Amphiregulin-Mediated Autocrine ErbB Signaling in Normal Human Keratinocytes  * A Novel Class of Fusion Polypeptides Inhibits Exocytosis  * Molecular Interactions between Matrilysin and the Matrix Metalloproteinase Inhibitor Doxycycline Investigated by Deuterium Exchange Mass Spe  * N-Methyl-D-aspartate and Brain-Derived Neurotrophic Factor Induce Distinct Profiles of Extracellular Signal-Regulated Kinase, Mitogen- and S  * Cotreatment with Suberanoylanilide Hydroxamic Acid and 17-Allylamino 17-demethoxygeldanamycin Synergistically Induces Apoptosis in Bcr-Abl+  * Selective Inhibition of Topoisomerase I and Various Steps of Spliceosome Assembly by Diospyrin Derivatives  * Sphingosine 1-Phosphate Receptors Mediate the Lipid-Induced cAMP Accumulation through Cyclooxygenase-2/Prostaglandin I2 Pathway in Human Cor  * Interaction of the Insulin Receptor with the Receptor-Like Protein Tyrosine Phosphatases PTP and PTP in Living Cells  * Involvement of Gi/o Proteins in Nerve Growth Factor-Stimulated Phosphorylation and Degradation of Tuberin in PC-12 Cells and Cortical Neuron  * Developmental Changes of GABA Synaptic Transient in Cerebellar Granule Cells  * Differential Sensitivity of Kir2 Inward-Rectifier Potassium Channels to a Mitochondrial Uncoupler: Identification of a Regulatory Site  * Glycogen Synthase Kinase 3 Activity Mediates Neuronal Pentraxin 1 Expression and Cell Death Induced by Potassium Deprivation in Cerebellar G  * -Arrestin 2-Dependent Angiotensin II Type 1A Receptor-Mediated Pathway of Chemotaxis  * -Arrestin-Dependent Spontaneous 1a-Adrenoceptor Endocytosis Causes Intracellular Transportation of -Blockers via Recycling Compartments  * Arsenite Inhibition of CYP1A1 Induction by 2,3,7,8-Tetrachlorodibenzo-p-dioxin Is Independent of Cell Cycle Arrest  * Regulation of Human Hepatic Hydroxysteroid Sulfotransferase Gene Expression by the Peroxisome Proliferator-Activated Receptor Transcription  * Trace Amines Depress GABAB Response in Dopaminergic Neurons by Inhibiting G--Gated Inwardly Rectifying Potassium Channels  * The CCR5 Receptor-Based Mechanism of Action of 873140, a Potent Allosteric Noncompetitive HIV Entry Inhibitor  * Residue 33 of Human Equilibrative Nucleoside Transporter 2 Is a Functionally Important Component of Both the Dipyridamole and Nucleoside Bin  * Cross-Resistance to Death Ligand-Induced Apoptosis in Cisplatin-Selected HeLa Cells Associated with Overexpression of DDB2 and Subsequent In  * The Xenobiotic-Metabolizing Enzymes Arylamine N-Acetyltransferases in Human Lens Epithelial Cells: Inactivation by Cellular Oxidants and UVB  * Nuclear Factor-B Decoy Oligodeoxynucleotides Prevent Acute Lung Injury in Mice with Cecal Ligation and Puncture-Induced Sepsis  * The New Anticonvulsant Retigabine Favors Voltage-Dependent Opening of the Kv7.2 (KCNQ2) Channel by Binding to Its Activation Gate  * Benzodiazepines Affect Channel Opening of GABAA Receptors Induced by Either Agonist Binding Site  * Anuroctoxin, a New Scorpion Toxin of the -KTx 6 Subfamily, Is Highly Selective for Kv1.3 over IKCa1 Ion Channels of Human T Lymphocytes  * The Size of a Single Residue of the Sulfonylurea Receptor Dictates the Effectiveness of KATP Channel Openers