现在位置：百拇书刊 > 国外期刊 > 临床调查学报 > 2005年.第8期 《临床调查学报》.2005年.第8期  * In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer  * Intensive insulin therapy protects the endothelium of critically ill patients  * Natural peptides selected by diabetogenic DQ8 and murine I-Ag7 molecules show common sequence specificity  * Autoantigen, innate immunity, and T cells cooperate to break B cell tolerance during bacterial infection  * PPAR regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1  * Induction of mucosal tolerance in Peyer‘s patch‘deficient, ligated small bowel loops  * The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages  * Saturated fat–rich diet enhances selective uptake of LDL cholesteryl esters in the arterial wall  * Human cardiac potassium channel DNA polymorphism modulates access to drug-binding site and causes drug resistance  * Impaired negative feedback suppression of bile acid synthesis in mice lacking Klotho  * Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice  * A mouse model of juvenile hemochromatosis  * Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload  * ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation  * The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice  * HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation  * Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients  * PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury  * Akt1/protein kinase B is critical for ischemic and VEGF-mediated angiogenesis  * Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure  * Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control  * The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis  * Of mice and men: the iron age  * A molecule’s right to choose: how diabetogenic class II MHC products bind peptides  * Weaving Klotho into bile acid metabolism  * You are right too!  * Insulin infusion in acute illness  * Spring brings breezes, wheezes, and pollen oxidases  * A new direction for gene therapy: intrathymic T cell–specific lentiviral gene transfer  * Akt1 in the cardiovascular system: friend or foe  * ATP-sensitive potassium channelopathies: focus on insulin secretion  * Chloride channel diseases resulting from impaired transepithelial transport or vesicular function  * Cardiac and skeletal muscle disorders caused by mutations in the intracellular Ca2+ release channels  * Genetics of acquired long QT syndrome  * Long QT syndrome: from channels to cardiac arrhythmias  * Sodium channel mutations in epilepsy and other neurological disorders  * Muscle channelopathies and critical points in functional and genetic studies  * Inherited disorders of voltage-gated sodium channels  * The channelopathies: novel insights into molecular and genetic mechanisms of human disease  * Thyrotropin receptor–associated diseases: from adenomata to Graves disease  * Tom Cruise is dangerous and irresponsible