现在位置：百拇书刊 > 国外期刊 > 联合生物学 > 2005年.第1期 《联合生物学》.2005年.第1期  * Catalytically inactive human cathepsin D triggers fibroblast invasive growth  * Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles  * Clathrin- and caveolin-1–independent endocytosis : entry of simian virus 40 into cells devoid of caveolae  * Receptor tyrosine phosphatase–dependent cytoskeletal remodeling by the hedgehog-responsive gene MIM/BEG4  * Concentric zones of active RhoA and Cdc42 around single cell wounds  * Molecular mechanisms of invadopodium formation : the role of the N-WASP–Arp2/3 complex pathway and cofilin  * New GABAergic interneurons in the adult neocortex and striatum are generated from different precursors  * The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex  * The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum  * Chromosome looping in yeast : telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization  * X chromosome choice occurs independently of asynchronous replication timing  * Myosin V attachment to cargo requires the tight association of two functional subdomains  * Viral killer toxins induce caspase-mediated apoptosis in yeast  * A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis  * Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells  * Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function  * ARFGAP1 plays a central role in coupling COPI cargo sorting with vesicle formation  * BACE overexpression alters the subcellular processing of APP and inhibits A deposition in vivo  * Generation of nonidentical compartments in vesicular transport systems  * Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast  * Actin-myosin–based contraction is responsible for apoptotic nuclear disintegration  * Nuclear transport of single molecules : dwell times at the nuclear pore complex  * Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis  * Spindle-independent condensation-mediated segregation of yeast ribosomal DNA in late anaphase  * The offloading model for dynein function : differential function of motor subunits  * Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model  * Cell growth–dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p  * A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleostemin  * Going in GTP cycles in the nucleolus  * CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex  * RPTP is essential for NCAM-mediated p59fyn activation and neurite elongation  * The PSD95–nNOS interface : a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death  * Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in  * HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway  * Specialized membrane-localized chaperones prevent aggregation of polytopic proteins in the ER  * Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation  * p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2  * Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins  * MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A  * Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription : implications for the epithelial–mesenchymal transition  * Centrosome fragments and microtubules are transported asymmetrically away from division plane in anaphase  * Hydrogen peroxide as a signal controlling plant programmed cell death  * Regulation of 51 integrin conformation and function by urokinase receptor binding