现在位置：百拇书刊 > 国外期刊 > 联合生物学 > 2005年.第8期 《联合生物学》.2005年.第8期  * PTP-1B is an essential positive regulator of platelet integrin signaling  * CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells  * The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila  * Regulatory mechanisms required for DE-cadherin function in cell migration and other types of adhesion  * A Rac switch regulates random versus directionally persistent cell migration  * Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells  * Assembly and trafficking of caveolar domains in the cell : caveolae as stable, cargo-triggered, vesicular transporters  * AtRMR1 functions as a cargo receptor for protein trafficking to the protein storage vacuole  * Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A  * Regulation of ubiquitin ligase dynamics by the nucleolus  * Support for the immortal strand hypothesis : neural stem cells partition DNA asymmetrically in vitro  * Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores  * Elevated expression of MITF counteracts B-RAF–stimulated melanocyte and melanoma cell proliferation  * Process outgrowth in oligodendrocytes is mediated by CNP, a novel microtubule assembly myelin protein  * -Catenin controls cell sorting at the notochord–somite boundary independently of cadherin-mediated adhesion  * Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast  * An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of endothelial cells  * Reaching out for signals : filopodia sense EGF and respond by directed retrograde transport of activated receptors  * An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway  * Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways  * Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex  * An ECT2–centralspindlin complex regulates the localization and function of RhoA  * Cyclic AMP and calcium interplay as second messengers in melatonin-dependent regulation of Plasmodium falciparum cell cycle  * Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle  * A glue for heterochromatin maintenance : stable SUV39H1 binding to heterochromatin is reinforced by the SET domain  * The origin recognition core complex regulates dendrite and spine development in postmitotic neurons  * FAPP2 is involved in the transport of apical cargo in polarized MDCK cells  * Dendrite development : a surprising origin  * The epidermal barrier function is dependent on the serine protease CAP1/Prss8  * Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain  * Essential role of CIB1 in regulating PAK1 activation and cell migration  * The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex  * The Rho kinases I and II regulate different aspects of myosin II activity  * Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca2+/calmodulin  * Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation  * The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis : Identification of the nuclear pore complex as a potential tar  * Viruses activate a genetically conserved cell death pathway in a unicellular organism  * Identification of FIP200 interaction with the TSC1–TSC2 complex and its role in regulation of cell size control  * Mammalian WDR12 is a novel member of the Pes1–Bop1 complex and is required for ribosome biogenesis and cell proliferation  * Dynamic formation of RecA filaments at DNA double strand break repair centers in live cells  * A local mechanism mediates NAD-dependent protection of axon degeneration  * sdfsfasfasfIndependent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells