事件相关电位P300和简易智能精神状态检查在轻微型肝性脑病检测中的价值
肝硬化;事件相关电位P300;智能精神状态检查;肝性脑病,事件相关电位P300和简易智能精神状态检查在轻微型肝性脑病检测中的价值,许统俭,陈剑群,董瑞国,李昕,耿德勤,通讯作者:,Valueofevent-relatedpotentialP300andmini-mentalstateexamina
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许统俭, 陈剑群, 董瑞国, 李昕, 耿德勤, 徐州医学院附属医院消化科 江苏省徐州市 221006
通讯作者: 许统俭, 221006, 江苏省徐州市淮海西路99号, 徐州医学院附属医院消化科. xzxtj@sina.com
电话: 0516-85802493
收稿日期: 2006-12-11 接受日期: 2007-01-10
Value of event-related potential P300 and mini-mental state examination in the diagnosis of minimal hepatic encephalopathy
Tong-Jian Xu, Jian-Qun Chen, Rui-Guo Dong, Xin Li, De-Qin Geng
Tong-Jian Xu, Jian-Qun Chen, Rui-Guo Dong, Xin Li, De-Qin Geng, Department of Digestology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou 221006, Jiangsu Province, China
Correspondence to: Tong-Jian Xu, Department of Digestology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou 221006, Jiangsu Province, China. xzxtj@sina.com
Received: 2006-12-11 Accepted: 2007-01-10
Abstract
AIM: To estimate the value of event related potential (ERP) P300 and mini-mental state examination (MMSE) in the detection of minimal hepatic encephalopathy (MHE).
METHODS: ERP P300 and somatosensory evoked potential (SEP) were examined, and MMSE were performed in 30 posthepatitic cirrhosis patients, and the occurrence of hepatic encephalopathy (HE) was observed 1 year after examination.
RESULTS: Abnormal ERP P300 occurred in 21 patients (70.0%), while abnormal SEP occurred in 11 (36.7%). MMSE scores less than 27 were found in 13 (43.3%) cases, and both or either abnormity of ERP P300 and MMSE were observed in 22 (73.3%). Ten cases (33 ......
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