通腑颗粒改善犬缺血再灌注状态下实施肠内营养时的小肠功能
通腑颗粒;缺血再灌注;肠内营养;肠耐受,胡森,夏斌,黎君友,邹晓防,周国勇,车晋伟,王海滨,于勇,通讯作者:,ImprovementeffectofTongfuparticlesongutfunctionintheprocessofente
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胡森, 夏斌, 黎君友, 邹晓防, 周国勇, 车晋伟, 中国人民解放军总医院第一附属医院烧伤研究所休克与多器官功能障碍实验室 北京市 100037
王海滨, 于勇, 中国人民解放军总医院第一附属医院检验科 北京市 100037
军队十一五专项课题资助项目, No. 06Z055
通讯作者: 胡森, 100037, 北京市阜成路51号, 中国人民解放军总医院第一附属医院烧伤研究所休克与多器官功能障碍实验室. hs82080@yanhoo.com.cn
电话: 010-66867397 传真: 010-68989391
收稿日期: 2007-01-22 接受日期: 2007-02-08
Improvement effect of Tongfu particles on gut function in the process of enteral nutrition following intestinal ischemia and reperfusion in dogsSen Hu, Hai-Bin Wang, Bin Xia, Yong Yu, Jun-You Li, Xiao-Fang Zou, Guo-Yong Zhou, Jin-Wei Che
Sen Hu, Bin Xia, Jun-You Li, Xiao-Fang Zou, Guo-Yong Zhou, Jin-Wei Che, Laboratory of Shock and Multiple Organ Dysfunction, Burn Institute, the First Hospital Affiliated to General Hospital of Chinese PLA, Beijing 100037, China
Hai-Bin Wang, Yong Yu, Department of Clinical Laboratory, the First Hospital Affiliated to General Hospital of Chinese PLA, Beijing 100037, China
Supported by the Special Foundation of the 11th Five-Year Plan for Military Medical Project, No. 06Z055
Correspondence to: Sen Hu, Laboratory of Shock and Multiple Organ Dysfunction, Burn Institute, the First Hospital Affiliated to General Hospital of Chinese PLA, 51 Fucheng Road, Beijing 100037, China. hs82080@yahoo.com.cn
Received: 2007-01-22 Accepted: 2007-02-08
Abstract
AIM: To investigate the effect of Tongfu particles (TF) on gut function during the administration of enteral nutrition (EN) following intestinal ischemia and reperfusion (I/R).
METHODS: Thirty-two male dogs were randomly and averagely divided into group A, B, C and D, received single EN, single I/R, I/R plus EN, and I/R plus EN plus TF, respectively. The intestinal I/R were achieved by clipping superior mesenteric artery (SMA) for 1 hours. EN was performed 4 hours after reperfusion. Gut intolerance was assessed by monitoring the symptoms of diarrhea and vomiting ......
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