结直肠高级别上皮内瘤变的临床分析38例
上皮内瘤变;结直肠;肿瘤;治疗,钟晓刚,黄顺荣,麦威,秦千子,殷舞,通讯作者:,Clinicopathologiccharacteristicsofhigh-gradecolorectalintraepithelialneoplasia:analysiso
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钟晓刚, 黄顺荣, 麦威, 秦千子, 广西壮族自治区人民医院胃肠外科 广西南宁市 530021
殷舞, 广西壮族自治区人民医院病理科 广西南宁市 530021
通讯作者: 钟晓刚, 530021, 广西南宁市桃源路6号, 广西壮族自治区人民医院胃肠外科. zhongxiaogang@csco.org.cn
电话: 0771-2186306
收稿日期: 2007-02-09 接受日期: 2007-03-07
Clinicopathologic characteristics of high-grade colorectal intraepithelial neoplasia: analysis of 38 cases
Xiao-Gang Zhong, Shun-Rong Huang, Wu Yin, Wei Mai, Qian-Zi Qin
Xiao-Gang Zhong, Shun-Rong Huang, Wei Mai, Qian-Zi Qin, Department of Gastrointestinal Surgery, Guangxi People’s Hospital, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Wu Yin, Department of Pathology, Guangxi People’s Hospital, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Correspondence to: Xiao-Gang Zhong, Department of Gastrointestinal Surgery, Guangxi People’s Hospital, Nanning 530021, Guangxi Zhuang Autonomous Region, China. zhongxiaogang@csco.org.cn
Received: 2007-02-09 Accepted: 2007-03-07
Abstract
AIM: To reveal the clinicopathological features of high-grade colorectal intraepithelial neoplasia and discuss treatment strategy.
METHODS: Thirty-eight cases of high-grade colorectal intraepithelial neoplasia diagnosed by colonoscopy biopsy were treated and followed up for 3 to 36 months. A retrospective review of clinical findings, endoscopic and histopathological features, and prognosis was used to determine appropriate treatment and follow-up for high-grade colorectal intraepithelial neoplasia.
RESULTS: Among the 38 patients, 17 underwent a preoperative endoscopic biopsy and agreed to a surgical operation; lesions in 19 cases were endoscopically resected, while the remaining 2 cases just agreed to being followed-up. Seventeen cases were diagnosed with a malignant carcinoma, and 21 eventually showed high-grade colorectal intraepithelial neoplasia. Pathological diagnosis pre- and post-treatment showed poor consistency; the Kappa value was 0 ......
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