复方五味子素B及其成分体外抑制胃癌细胞的增殖
五味子乙素;芦荟大黄素;黄芪多糖;MTT法;胃癌,刘晓霓,张承玉,李月珍,金秀东,郑学芝,李丽,通讯作者:,InhibitoryeffectsofthecomponentsofSchisandrincompoundongastriccancercel
 |
| 第1页 |
参见附件(852KB，4页)。
刘晓霓, 张承玉, 李月珍, 金秀东, 郑学芝, 李丽, 牡丹江医学院生理教研室 黑龙江省牡丹江市 157011
黑龙江省自然科学基金资助项目, No. TD2005-01
黑龙江省卫生厅课题资助项目, No. 2006-391
通讯作者: 刘晓霓, 157011, 黑龙江省牡丹江市, 牡丹江医学院生理教研室. liuxiaoni888@yahoo.com.cn
电话: 0453-6582156-3384
收稿日期: 2007-03-09 修回日期: 2007-08-06
Inhibitory effects of the components of Schisandrin compound on gastric cancer cells in vitro
Xiao-Ni Liu, Cheng-Yu Zhang, Yue-Zhen Li, Xiu-Dong Jin, Xue-Zhi Zheng, Li Li
Xiao-Ni Liu, Cheng-Yu Zhang, Yue-Zhen Li, Xiu-Dong Jin, Xue-Zhi Zheng, Li Li,Department of Physiology, Mudanjiang Medical College, Mudanjiang 157011, Heilongjiang Province, China
Supported by:the Natural Science Foundation of Heilongjiang Province, No. TD2005-01; Heilongjiang Health Department Research Fund, No. 2006-391
Correspondence to:Xiao-Ni Liu, Department of Physiology, Mudanjiang Medical College, Mudanjiang 157011, Heilongjiang Province, China. liuxiaoni888@yahoo.com.cn
Received:2007-03-09 Revised:2007-08-06
Abstract
AIM: To screen the constituent parts of Schi-sandrin compound, and to ascertain the best composition by comparing the inhibitory effects of Schisandrin compound and its ingredients on gastric cancer cells in vitro.
METHODS: An orthogonal design was used to screen for the best composition of Schisandrin compound. MTT assay was used to examine the inhibitory effects of Schisandrin compound and its ingredients on gastric cancer cells. Data from 10 groups were analyzed: normal control (medium), negative control (2 g/L DMSO), positive control (50 mg/L 5-fluorouracil), low concentration Schisandrin (50 mg/L), high concentration Schisandrin (100 mg/L), low concentration aloe emodin (50 mg/L), high concentration aloe emodin (100 mg/L), low concentration Astragalus polysaccharides (50 mg/L), high concentration Astragalus polysaccharides (200 mg/L) and Schisandrin compound.
RESULTS: The best combinations of Schisandrin, aloe emodin and Astragalus polysaccharides were 100 mg/L, 50 mg/L and 50 mg/L, respectively ......
您现在查看是摘要介绍页，详见PDF附件(852KB，4页)。