下调XIAP表达增强化疗药物诱导胃癌细胞凋亡的作用
胃癌;XIAP基因;反义RNA;基因表达;细胞凋亡,郑丽端,童强松,汪良,董继华,侯晓华,通讯作者:,Effectsofdown-regulatingexpressionofX-linkedinhibitorofapoptosisonche
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郑丽端, 华中科技大学同济医学院附属协和医院病理科 湖北省武汉市 430022
童强松, 汪良, 华中科技大学同济医学院附属协和医院外科 湖北省武汉市 430022
董继华, 华中科技大学同济医学院附属协和医院中心实验室 湖北省武汉市 430022
侯晓华, 华中科技大学同济医学院附属协和医院消化内科 湖北省武汉市 430022
郑丽端, 2005年华中科技大学同济医学院博士研究生, 主治医师, 主要从事消化系统疾病的分子病理研究.
国家自然科学基金资助项目, No. 30600278
教育部新世纪优秀人才支持计划资助项目, No. NCET- 06-0641
通讯作者: 童强松, 430022, 湖北省武汉市, 华中科技大学同济医学院附属协和医院外科. qs_tong@hotmail.com
电话: 027-85726129
收稿日期: 2007-05-28 修回日期: 2007-09-27
Effects of down-regulating expression of X-linked inhibitor of apoptosis on chemotherapy-induced apoptosis of gastric cancer cells
Li-Duan Zheng, Qiang-Song Tong, Liang Wang, Ji-Hua Dong, Xiao-Hua Hou
Li-Duan Zheng, Department of Pathology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Qiang-Song Tong, Liang Wang, Department of Surgery, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Ji-Hua Dong, Department of Central Laboratory, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Pro-vince, China
Xiao-Hua Hou, Department of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Pro-vince, China
Supported by: National Natural Science Foundation of China, No. 30600278 and Program for New Century Excellent Talents in University, No. NCET-06-0641
Correspondence to: Dr. Qiang-Song Tong, Department of Surgery, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China. qs_tong@hotmail.com
Received: 2007-05-28 Revised: 2007-09-27
Abstract
AIM: To observe the effects of down-regulating expression of X-linked inhibitor of apoptosis (XIAP) on the chemotherapeutic sensitivity of gastric cancer cells ......
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