热疗联合放疗治疗老龄贲门癌33例
贲门肿瘤,放射疗法;热疗;高龄,周健,卢绪菁,通讯作者:,Efficacyofcombinedradiationandhyperthermiaforcardiaccarcinomainolderpatients:ananalysisof33cases,Jian
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周健, 卢绪菁, 苏州大学附属常州肿瘤医院放疗科 江苏省常州市 213001
通讯作者: 周健, 213001, 江苏省常州市怀德南路1号, 苏州大学附属常州肿瘤医院放疗科. zhou-jian@csco.org.cn
电话: 0519-86868236
收稿日期: 2007-07-03 修回日期: 2007-10-08
Efficacy of combined radiation and hyperthermia for cardiac carcinoma in older patients: an analysis of 33 cases
Jian Zhou, Xu-Jing Lu
Jian Zhou, Xu-Jing Lu, Department of Radiation Oncology, Changzhou Cancer Hospital, Suzhou University, Changzhou 213001, Jiangsu Province, China
Correspondence to: Jian Zhou, Department of Radiation Oncology, Changzhou Cancer Hospital, Suzhou University, 1 South Huaide Road, Changzhou 213001, Jiangsu Province, China. zhou-jian@csco.org.cn
Received: 2007-07-03 Revised: 2007-10-08
Abstract
AIM: To evaluate the efficacy of thermo-radiotherapy for older patients with cardiac carcinoma.
METHODS: Sixty-four older patients with cardiac carcinoma were randomly divided into two groups, among which 31 were treated with simple radiotherapy and 33 with thermo-radiotherapy. Both groups received normal irradiation of 60–66 Gy/6–6.5 W. For the combination group, heating was administered within 1 hour after completion of radiation, with local temperature ranging from 40 to 43℃. Each session took 40 min and two sessions were given every week. Ten sessions in total were given.
RESULTS: For the simple radiotherapy group, the complete response rate was 25.81%, total response rate was 67.74%, and 1-, 2- and 3-yearsurvival rates were 58.06%, 38.71% and 19.35% respectively, with a median survival time of 15 mo. In the thermo-radiotherapy group, the complete response rate was 42.42%, total response rate was 90.91%, and the 1-, 2- and 3 years survival rates were 72.72%, 51.51% and 33.33%, respectively, with a median survival time of 27 months. A significant difference was observed between the two groups (P < 0.05). Side effects of radiotherapy were not different between the two groups ......
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