利胆化瘀片的利胆消炎作用
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杨 琼, 陆付耳, 徐丽君, 高志强, 王开富
利胆化瘀片;利胆;抗炎,杨琼,陆付耳,徐丽君,高志强,王开富,通讯作者:,Cholagogicandanti-inflammatoryeffectsofLidanHuayutablets,QiongYang,Fu-ErLu,Li-JunXu,Zhi-QiangGao,K
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杨琼, 陆付耳, 徐丽君, 高志强, 王开富, 华中科技大学同济医学院附属同济医院中西医结合研究所 湖北省武汉市 430030
武汉市技术创新与产业化重大专项攻关课题资助项目, No. 2002600513415
通讯作者: 陆付耳, 430030, 湖北省武汉市解放大道1095号, 华中科技大学同济医学院附属同济医院中西医结合研究所.
felu@tjh.tjmu.edu.cn
电话: 027-83663237
收稿日期: 2007-05-11 修回日期: 2007-10-08
Cholagogic and anti-inflammatory effects of Lidan Huayu tablets
Qiong Yang, Fu-Er Lu, Li-Jun Xu, Zhi-Qiang Gao, Kai-Fu Wang
Qiong Yang, Fu-Er Lu, Li-Jun Xu, Zhi-Qiang Gao, Kai-Fu Wang, Institute of Integrative Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, Hubei Province, China
Supported by: the Key Research Projects of Wuhan Municipal Technical Innovation and Industrialization, No. 2002600513415
Correspondence to: Dr. Fu-Er Lu, Institute of Integrative Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. felu@tjh.tjmu.edu.cn
Received: 2007-05-11 Revised: 2007-10-08
Abstract
AIM: To observe the cholagogic and anti-inflammatory effects of Lidan Huayu tablets in experimental animals.
METHODS: Murine bile output was measured to observe the effects of Lidan Huayu tablets on bile secretion and the composition or ratio of bilirubin and bile acids. Ursodeoxycholic acid was used as a positive control. The anti-inflammatory action of Lidan Huayu tablets was observed in a model of xylene-induced auricular swelling and acetic-acid-induced celiac microcapillary permeability in mice. Aspirin was used as a positive control.
RESULTS: Compared with the normal saline group, the bile secretory volume in the Lidan Huayu tablet treatment group increased significantly in healthy rats in a dose-dependent manner, and this facilitating effect on bile excretion remained for > 3 h ......
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