早期肠内营养联合肠屏障保护剂治疗急性重症胰腺炎64例
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王远志, 丁岩冰, 吴 健, 邓 彬, 肖炜明
早期肠内营养;肠屏障保护剂;重症胰腺炎;鼻空肠管,王远志,丁岩冰,吴健,邓彬,肖炜明,通讯作者:,Treatmentof64casessevereacutepancreatitiswithearlyenteralnutritionandinte
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王远志, 丁岩冰, 吴健, 邓彬, 肖炜明, 扬州市第一人民医院消化内科 江苏省扬州市 225001
通讯作者: 王远志, 225001, 江苏省扬州市泰州路45号, 扬州市第一人民医院消化内科. meteorcloud@yeah.net
电话: 0514-87907336
收稿日期: 2007-04-26 修回日期: 2007-11-08
Treatment of 64 cases severe acute pancreatitis with early enteral nutrition and intestinal barrier protective agents
Yuan-Zhi Wang, Yan-Bing Ding, Jian Wu, Bin Deng, Wei-Ming Xiao
Yuan-Zhi Wang, Yan-Bing Ding, Jian Wu, Bin Deng, Wei-Ming Xiao, Department of Gastroenterology, First People’s Hospital of Yangzhou city, Yangzhou 225001, Jiangsu Province, China
Correspondence to: Yuan-Zhi Wang, Department of Gastroenterology, First People's Hospital of Yangzhou city, Yangzhou 225001, Jiangsu Province, China. meteorcloud@yeah.net
Received: 2007-04-26 Revised: 2007-11-08
Abstract
AIM: To evaluate the efficacy of early enteral nutrition and intestinal barrier protective agents on severe acute pancreatitis (SAP).
METHODS: Sixty-four patients with SAP were randomly divided into groups A, B and C. Group A was given conventional therapy, group B enteral nutrition by nasogastric feeding, and group C enteral nutrition and intestinal barrier protective agents by nasogastric feeding. We measured the recovery time from symptoms, physical signs and laboratory parameters [white blood cell count (WBC), C-reactive protein (CRP) and serum amylase], changes in body weight and serum albumin, cost of hospitalization and length of stay.
RESULTS: Recovery time from symptoms, physical signs and laboratory parameters in group B was significantly shorter than that in group A (P< 0.05). Cost of hospitalization and length of stay in group B were better than those in group A (P < 0.05). Recovery time of CRP and WBC in group C was significantly shorter than that in group B (P < 0.05). Average daily hospitalization cost was comparable in the three groups.
CONCLUSION: Treatment of SAP with early enteral nutrition and intestinal barrier protective agents can improve nutrition, speed up symptom recovery, shorten length of stay and reduce medical costs ......
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