食物不耐受与腹泻型肠易激综合征的关系
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张旭东, 邓 敏, 李 梅, 王晓玲
食物不耐受;腹泻型肠易激综合征;饮食治疗,张旭东,邓敏,李梅,王晓玲,通讯作者:,Foodintoleranceanddiarrhea-dominantirritablebowelsyndrome,Xu-DongZhang,MinDeng,MeiLi,X
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张旭东, 邓敏, 李梅, 扬州大学临床医学院老年医学科 江苏省扬州市 225001
王晓玲, 扬州大学临床医学院临床检测中心 江苏省扬州市 225001
通讯作者: 张旭东, 225001, 江苏省扬州市南通西路98号, 扬州大学临床医学院老年医学科. zhangxd0448@163.com
电话: 0514-87937511
收稿日期: 2007-09-08 修回日期: 2007-12-20
Food intolerance and diarrhea-dominant irritable bowel syndrome
Xu-Dong Zhang, Min Deng, Mei Li, Xiao-Ling Wang
Xu-Dong Zhang, Min Deng, Mei Li, Department of Geratology, Yangzhou University College of Clinical Medicine, Yangzhou 225001, Jiangsu Province, China
Xiao-Ling Wang, Clinical Testing Center, Yangzhou University College of Clinical Medicine, Yangzhou 225001, Jiangsu Province, China
Correspondence to: Xu-Dong Zhang, Department of Geratology, Yangzhou University College of Clinical Medicine, 98 Nantong Western Road Yangzhou 225001, Jiangsu Province, China. zhangxd0448@163.com
Received: 2007-09-08 Revised: 2007-12-20
Abstract
AIM: To explore the relationship between food intolerance and diarrhea-dominant irritable bowel syndrome (dIBS).
METHODS: In 68 patients with Rome II dIBS, we semi-quantitatively measured specific IgG antibody to 14 food allergens in the serum, then eliminated the corresponding food. After 8 weeks, we observed changes in symptom frequency and disease severity index.
RESULTS: Compared with the normal control group, 48 patients with dIBS appeared positive to at least one food allergen, with a positive rate of 70.6%, and the difference was significant (P < 0.05). After 8 weeks diet therapy, clinical symptoms of dIBS were significantly relieved in 29 patients who were positive for >2 food allergens ......
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