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作者：汤华琴 赵 焰 张秀珍 邹家立 廖年生
鱼油|微囊|复凝聚法,.
作者：汤华琴 赵 焰 张秀珍 邹家立 廖年生
单位：汤华琴(山东省威海市文登中心医院 威海264400)；赵 焰 张秀珍 邹家立(山东医科大学药学系)；廖年生(江西省赣南制药厂)
关键词：鱼油；微囊；复凝聚法
摘要 本文采用复凝聚法以阿拉伯胶和明胶为包裹材料 摘要 本文采用复凝聚法以阿拉伯胶和明胶为包裹材料,将鱼油微囊化后,再装入硬胶囊中,并对其含量测定方法、包封率、稳定性和释放度等进行了实验研究。包封率达85%以上,微囊T1/2为720d,微囊释放度8h为89.88%;本法提高了鱼油的稳定性。
Study on capsules fish oil microencapsule
Tang Huaqin,Zhao Yan,Liao Niansheng,et al (Wendeng Central Hospital,Weihai 264400)
The microencapsulated fish oil was obtained by multiple coacervation with acacia and gelatin as capsule wall materials,and than filled in hard capsules to prepare a solid oral preparation of fish oil.The encapsulated ratio,assay method,stability and release rate were studied.The results provide foundation for further development and application of fish oil. ......
单位：汤华琴(山东省威海市文登中心医院 威海264400)；赵 焰 张秀珍 邹家立(山东医科大学药学系)；廖年生(江西省赣南制药厂)
关键词：鱼油；微囊；复凝聚法
摘要 本文采用复凝聚法以阿拉伯胶和明胶为包裹材料 摘要 本文采用复凝聚法以阿拉伯胶和明胶为包裹材料,将鱼油微囊化后,再装入硬胶囊中,并对其含量测定方法、包封率、稳定性和释放度等进行了实验研究。包封率达85%以上,微囊T1/2为720d,微囊释放度8h为89.88%;本法提高了鱼油的稳定性。
Study on capsules fish oil microencapsule
Tang Huaqin,Zhao Yan,Liao Niansheng,et al (Wendeng Central Hospital,Weihai 264400)
The microencapsulated fish oil was obtained by multiple coacervation with acacia and gelatin as capsule wall materials,and than filled in hard capsules to prepare a solid oral preparation of fish oil.The encapsulated ratio,assay method,stability and release rate were studied.The results provide foundation for further development and application of fish oil. ......