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作者：李荣亮 李盛余 周淑群
地戈辛|放免法|血药浓度监测
作者：李荣亮 李盛余 周淑群
单位：李荣亮 李盛余 柳州 广西龙泉山医院；周淑群 柳州 广西柳州市工人医院
关键词：地戈辛；放免法；血药浓度监测
中国现代应用药学990230摘要 目的：监测地戈辛血药浓度。方法：采用放免法监测746例地戈辛治疗慢性心功能不全病人的血药浓度。结果：血药浓度在治疗范围者325例、偏低者99例、高者322例，大于治疗范围者中有12例出现中毒症状。结论：监测地戈辛血药浓度可作为判断药物疗效和中毒的客观指标。
Analysis of digoxine plasma concentration of 746 patients determined by radioimmunoassay
Li Rongliang(Li RL),Li Shengyu(Li SY),Zhou Shuqun(Zhou SQ)(Guangxi Longquanshan Hospital,Liuzhou 545005)
ABSTRACT OBJECTIVE：To monitor digoxine plasma concentration.METHODS:Digoxine plasma concentralion of 746 chronic cardiac insufficiency patients were monitored by radioimmunoassay.RESULTS:There were 325 patients′ plasma concentration in therapeutic range,99 patients plasma concentration belowe therapeutic range,322 patients′ plasma concentration above therapeutic range.There were 12 patients whose plasma concentration above therapeutic range,presenting toxic symptom.CONCLUSION:Monitoring digoxine plasma concentration might be as an objective criterion of therapeutic effect and toxicosis. ......
单位：李荣亮 李盛余 柳州 广西龙泉山医院；周淑群 柳州 广西柳州市工人医院
关键词：地戈辛；放免法；血药浓度监测
中国现代应用药学990230摘要 目的：监测地戈辛血药浓度。方法：采用放免法监测746例地戈辛治疗慢性心功能不全病人的血药浓度。结果：血药浓度在治疗范围者325例、偏低者99例、高者322例，大于治疗范围者中有12例出现中毒症状。结论：监测地戈辛血药浓度可作为判断药物疗效和中毒的客观指标。
Analysis of digoxine plasma concentration of 746 patients determined by radioimmunoassay
Li Rongliang(Li RL),Li Shengyu(Li SY),Zhou Shuqun(Zhou SQ)(Guangxi Longquanshan Hospital,Liuzhou 545005)
ABSTRACT OBJECTIVE：To monitor digoxine plasma concentration.METHODS:Digoxine plasma concentralion of 746 chronic cardiac insufficiency patients were monitored by radioimmunoassay.RESULTS:There were 325 patients′ plasma concentration in therapeutic range,99 patients plasma concentration belowe therapeutic range,322 patients′ plasma concentration above therapeutic range.There were 12 patients whose plasma concentration above therapeutic range,presenting toxic symptom.CONCLUSION:Monitoring digoxine plasma concentration might be as an objective criterion of therapeutic effect and toxicosis. ......