使用汇总分析进行临床决策(6)
作者们总结时指出，这些分析说明冠心病事件危险的下降是明确和一致的。也是独立于年龄和性别之外的，所有组的冠心病事件的发生均降低约30%。在这些分析基础上，他们提议重新审查胆固醇普查指南的保险覆盖问题。
结论
汇总分析是用以分析从一组类似的临床试验中得来的资料的一种有用且已被广泛接受的方法。其结论的一致性取决于原始的临床试验的质量以及他们是否足够相似以便综合。已有测试研究均一性和发表偏倚的统计学方法。如以上所述，汇总分析可用于扩大我们对已有资料的理解，以便作出临床和政策的决策，也为未来的研究提出新的问题。
参考文献
1. Mendelson YT.Keeping up with the medical literature.In:Friedland DJ, ed.Evidence-based medicine:a framework for clinical practice.Stamford:Appleton Lange, 1998.62-73.
2. Davidoff F.Report on The 7th international cochrane colloquium-rome, 5-9 October 1999.Ann Int Med, 131:64-70.
3. Petitti DB.Meta-analysis ,decision analysis and cost-effectiveness analysis .New York:Oxford University Press,1994
4. Muir Gray JA.Evidence-based healthcare:how to make health policy and management decisions .London:Churchill Livingstone,1997,62-81.
5. Dickersin K,Berlin JA.Meta-analysis:state-of-the -science.Epidemic Rev,1992,14:154-175.
6. Lau J, Ioannidis JPA, Schmid CH.Quantitative synthesis in systematic reviews. Ann Int Med, 1997,127:820-827.
7. LaRosa JC,Jiang H,Vupputuri S.Effect of statins on risk of cor4onary heart disease.JAMA,1999,282:2340-2346, http://www.100md.com(Audrey F.Jakubowski,Ph.D.)
结论
汇总分析是用以分析从一组类似的临床试验中得来的资料的一种有用且已被广泛接受的方法。其结论的一致性取决于原始的临床试验的质量以及他们是否足够相似以便综合。已有测试研究均一性和发表偏倚的统计学方法。如以上所述，汇总分析可用于扩大我们对已有资料的理解，以便作出临床和政策的决策，也为未来的研究提出新的问题。
参考文献
1. Mendelson YT.Keeping up with the medical literature.In:Friedland DJ, ed.Evidence-based medicine:a framework for clinical practice.Stamford:Appleton Lange, 1998.62-73.
2. Davidoff F.Report on The 7th international cochrane colloquium-rome, 5-9 October 1999.Ann Int Med, 131:64-70.
3. Petitti DB.Meta-analysis ,decision analysis and cost-effectiveness analysis .New York:Oxford University Press,1994
4. Muir Gray JA.Evidence-based healthcare:how to make health policy and management decisions .London:Churchill Livingstone,1997,62-81.
5. Dickersin K,Berlin JA.Meta-analysis:state-of-the -science.Epidemic Rev,1992,14:154-175.
6. Lau J, Ioannidis JPA, Schmid CH.Quantitative synthesis in systematic reviews. Ann Int Med, 1997,127:820-827.
7. LaRosa JC,Jiang H,Vupputuri S.Effect of statins on risk of cor4onary heart disease.JAMA,1999,282:2340-2346, http://www.100md.com(Audrey F.Jakubowski,Ph.D.)