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编号:10483802
卒中后抑郁
http://www.100md.com 2004年10月10日 本会
     中山大学附属第三医院神经病学科 (510660)

    一、常见的脑血管病并发症

    1924年Bleuler首先报道

    二、PSD的发生率

    20%-80%

    三、PSD与病灶部位

    左半球损害

    左前皮质损害

    左前半球损害

    四、PSD与认知功能

    卒中

    认知功能

    抑郁

    五、PSD与神经功能缺损程度

    诱发心理反应性抑郁?

    延缓神经功能恢复

    六、PSD与躯体疾病

    既往的疾病

    合并的疾病

    应激性反应

    七、PSD与其他因素

    遗传

    抑郁病史

    社会活动能力

    家庭和社会支持

    护理的满意程度

    八、PSD的发病机制

    原发性内源机制学说

    反应性机制学说

    九、PSD对卒中预后的影响

    延缓功能恢复

    生存质量下降

    病死率增高

    十、PSD的诊断

    抑郁的共性

    诊断标准

    十一、PSD的鉴别诊断

    特异性生物学指标

    急性期伴意识障碍和失语

    康复期有智能障碍

    十二、PSD治疗概况

    药物治疗

    心理治疗

    电治疗

    Post-Stroke Depression

    HU Xueqiang

    Neurology Department the 3rd Affiliated Hospital of Zhongshan University

    1. Common sequela of cerebral vascular disease

    1924 , Bleuler

    2. Prevalence rate

    20%-80%

    3. PSD & Location of lesions

    Left hemisphere damage

    Left anterior cortical damage

    Left anterior hemisphere damage

    4. PSD & Cognitive function

    Stroke

    Cognition

    Depression

    5. PSD& degree of neurological dysfunction

    Induced psychological reactive depression?

    Impaired function recovery

    6. PSD & Somatic disease

    Personal history

    Medical comorbidity

    Stress reaction

    7. PSD & Other risk factors

    Genetics

    History of depression

    Ability of social activities

    Support from family and society

    Nursing

    8. Pathogenesis

    Primary endogenous mechanism

    Reactive mechanism

    9. Impact on outcomes of stroke

    Impaired functional recovery

    Poor quality of life

    High mortality risk

    10. Diagnosis

    Common features of depression

    Diagnostic criteria

    11. Differential diagnosis

    Specific biological marker

    Cognitive and language deficits in the acute phase

    Intellectual decline in the acute phase

    12. Treatment options

    Antidepressant medications

    Psychological counseling

    Electroconvulsive therapy (ECT)

    13. Prospect on future, http://www.100md.com(胡学强)