肝细胞癌术后复发的临床病理
肝肿瘤,外科学癌，肝细胞,外科学肿瘤复发，局部预后危险因素,项目负责人,Clinicopathologicriskfactorsandprognosticevaluationinhepatocellularcarcinomarecurrenceaftersurgery,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subjectheadings,摘,要
第二军医大学 1病理学教研室 2东方肝胆外科研究所 上海市 2004333启东肝癌防治研究所 江苏省启东市 226200
*国家自然科学基金资助项目(No.3880388)
戴益民，男，1934-02-17生，浙江省瑞安市人，汉族. 1961年上海第二军医大学医疗专业毕业，1981年上海医科大学肿瘤医院高级病理师资班毕业，病理学教授，教研室副主任，上海市病理学会委员，国家自然科学基金委评委，主要从事肿瘤病理与分子病理研究，发表论文30篇，参与编著3部.
项目负责人 戴益民，上海市杨浦区翔殷路800号.
Tel: 021-65347018-71361.收搞日期 1996-09-09 接受日期 1996-09-28
Clinicopathologic risk factors and prognostic evaluation in hepatocellular carcinoma recurrence after surgery
Yi-Min Dai, Han Chen, Neng-Jin Wang, Can-Rong Ni, Wen-Ming Cong and Song-Ping Zhang
Department of Pathology, Second Military Medical University, Shanghai 200433, China
Abstract
AIM To analyze the clinicopathologic risk factors in hepatoc ellular carcinoma recurrence after surgery.
METHODS Significance test (χ2 and Student t test) of the single and multiple factors, and Wilcoxon Cox tropic examination were used, a retrospective clinicopathologic analysis was made in 156 cases of hepatocellular carcinoma after hepatectomy.
RESULTS Of the 156 cases, 68.4%, 57.3%, 46.7%, 31.5% and 28.6% had 1, 2, 3, 4 and 5 postoperative tumorfree years respectively with a total recurrence rate of 53.2% (83/156). In the 83 recurrent cases, 65 were of intrahepatic sabclinical type, with a reresection rate of 78.3% (65/83). The relevant factors involved in recurrence were: males, tumor number and size, capsule infiltration, portal veins involvement, etc. Those factors obviously influenced the prognosis of the patients with postoperative hepatocellular carcinoma (P<0.05). 63.1% tumor nodes (41/65) of recurrent liver cancinomas were located at the ipsilateral segment of the primary ones. ......
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