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编号:10695043
肝硬变大鼠食管一氧化氮含量与血流动力学改变
http://www.100md.com 1997年9月15日 《世界华人消化杂志》 1997年第9期
肝硬变,代谢;食管,化学;一氧化氮,代谢;血液动力学,项目负责人,Nitricoxideconcentrationofesophagealtissuesandhemodynamicsincirrhoticrats,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subjectheadings,摘,要,目的,方法,结果,结论
     上海第二医科大学附属仁济医院 上海市消化疾病研究所 上海市 200001

    黄颖秋,男,1962-03-30生,辽宁省本溪市人,汉族. 1985年锦州医学院医疗系毕业. 上海第二医科大学仁济医院消化所医学硕士,副主任医师,主要从事胃肠病及肝病的诊治研究,发表论文、综述、译文等25篇.

    项目负责人 黄颖秋,上海市山东中路145号.

    Tel: 021-63260930-2001,Fax: 021-637300455. 收搞日期 1996-12-20 接受日期 1997-01-21

    Nitric oxide concentration of esophageal tissues and hemodynamics in cirrhotic rats

    
Ying_Qiu Huang, De_Zhong Zhang, Jian_Zhong Mo, Rong_Rong Li and Shu_Dong Xiao

    Shanghai Institute of Digestive Diseases, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China

    Abstract

    AIM
To investigate the changes of nitric oxide concentration in esophageal tissues of serum and hemodynamics in cirrhotic rats.

    METHODS Cirrhosis model was induced in made SD rats by injection of 60% CCl4 oily solution subcutaneously. There were 8 cirrhotic rats in experimental group and 8 normal SD rats served as controls. Mean arterical pressure (MAP), portalvein pressure (PVP), cardiac output (CO), cardiac index(CI), splanchnic vascular resistance (SVR) and splanchnic blood flow(SBF) were determined in using 57Co_labled microsphere technique. In addition, concentration of nitric oxide in esophageal ussues or serum were also measured using a fluorometric assay. ......

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