结肠直肠肿瘤_治疗;基因疗法;胸苷激酶

逆转录病毒载体介导的HSVtk基因联合5-FU治疗实验性大肠癌

http://www.100md.com 2001年2月15日《世界华人消化杂志》 2001年第2期

结肠直肠肿瘤,治疗;基因疗法;胸苷激酶,遗传学;氟尿嘧啶,治疗应用;疱疹病毒科;更西罗韦,项目负责人,Correspondenceto,Herpessimplexvirusthymidinekinase,ganciclovirsystemcombinedwith5-FUforthetreatmentofexper

     ¹中国人民解放军第一军医大学珠江医院普外科 广东省广州市 510282

    ²中国人民解放军第一军医大学药理教研室广东省广州市 510515

    钱伟峰，男，1972-10-01生，江苏省武进市人，汉族. 1995年第一军医大学本科毕业，现为硕士生，主要从事胃肠肿瘤诊治的研究，发表论文11篇.

    项目负责人 钱伟峰，510282，广东省广州市，中国人民解放军第一军医大学珠江医院普外科.

    ¹Department of General Surgery, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, Guangdong Province, China

    ²Department of Pharmacology, First Military Medical University, Guangzhou 510515, Guangdong Province, China

    Correspondence to Wei-Feng Qian, Department of General Surgery, Zhujiang Hospital, First Military Medical University,Guangzhou 510282, Guangdong Province, China

    Tel. 0086-20-85143549

    Received 2000-07-26 Accepted 2000-09-18

    Herpes simplex virus thymidine kinase/ganciclovir system combined with 5-FU for the treatment of experimental colorectal cancer

    Wei-Feng Qian¹, Zong-Hai Huang¹ and De-Biao Chi²



    Abstract

    AIM To study the effect of synergistic use of herpes simplex virus thymidine kinase/ganciclovir (HSVtk/GCV) and 5-FU for the treatment of experimental colorectal cancer (CRC). ......

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