刘建平,朱兆华,中山大学附属第二医院消化内科 广东省广州市 510120

    刘建平,男,1972-11-07生,湖南省新化县人,汉族,1995年苏州医学院毕业,2002-06中山大学医学院硕士毕业,住院医师,主要从事消化道肿瘤诊治的研究.

    项目负责人:朱兆华,510120,广东省广州市沿江西路107号,中山大学附属第二医院消化内科.

    电话:020-81332490

    收稿日期:2002-07-16 接受日期:2002-07-30

    Correlation of COX-2 expression and clinicopathological features of colorectal cancer

    Jian-Ping Liu,Zhao-Hua Zhu

    Jian-Ping Liu, Zhao-Hua Zhu, Department of Gastroenterology,The second affiliated Hospital, Sun Yat-Sen University,Guangzhou 510120,Guandong Province,China

    Correspondence to:Zhao-Hua Zhu, Department of Gastroenterology,The second affiliated hospital,Sun Yat-Sen University,107 YangJiang lu, Guangzhou 510120,Guandong Province,China

    Received:2002-07-16 Accepted:2002-07-30

    AbstractAIM:To investigate the expression of COX-2 on different stages of colorectal cancer and the correlation between the expression of COX-2 and its clinicopathological features.

    METHODS:The expression of COX-2 was determined by immunohistochemical staining in seventy-six surgical specimens of colorectal cancer (late stage 44 and early stage 32), 33 adenomas and 18 normal colonic mucosal tissues were biopsied endocscopically. The correlation of COX-2 with the survival rate was evaluated with Kaplan-Meier survival curves and Cox proportional hazards regression. ......