TGIF反义寡核苷酸对胃癌细胞增生和凋亡的影响
胡忠良,文继舫,柳洋,王宽松,郑晖,傅春燕,项目负责人,:,EffectsofTGIFantisenseoligonucleotideonproliferationandapoptosisofgastriccarcinomacells,Correspondenceto:,Abstract,摘要,目的,方法,结果,结论,:,0,引言,1,材料和方法
胡忠良, 文继舫, 柳洋, 王宽松, 郑晖, 傅春燕, 中南大学基础医学院病理学教研室 湖南省长沙市 410078胡忠良, 男, 1973-02-05生, 湖南省衡山县人, 汉族. 1997年湖南医科大学学士, 中南大学基础医学院病理学教研室在职博士生, 主要从事胃肠肿瘤研究.
项目负责人: 文继舫, 410078, 湖南省长沙市湘雅路88号, 中南大学基础医学院病理学教研室. jifangwen@hotmail.com
电话: 0731-2650400 传真: 0731-2650400
收稿日期: 2003-07-15 接受日期: 2003-08-28
Effects of TGIF antisense oligonucleotide on proliferation and apoptosis of gastric carcinoma cells
Zhong-Liang Hu, Ji-Fang Wen, Yang Liu, Kuan-Song Wang, Hui Zhen, Chun-Yan Fu
Zhong-Liang Hu, Ji-Fang Wen, Yang Liu, Kuan-Song Wang, Hui Zhen, Chun-Yan Fu, Department of Pathology, Basic Medical Institute, Central South University, Changsha 410078, Hunan Province, China
Correspondence to: Ji-Fang Wen, Department of Pathology, Basic Medical Institute, Central South University, 88 Xiangya Road, Changsha 410078, Hunan Province, China. jifangwen@hotmail.com
Received: 2003-07-15 Accepted: 2003-08-28
AbstractAIM: TG interacting factor (TGIF) can inhibit both TGF-b and retinoid signaling pathways, moreover, the activation of MAPK pathway can lengthen its half life. However, its role in carcinogenesis is still unclear. Thus we attempt to investigate the effect of TGIF antisense oligodeoxynucleo-tide (ASDON) on proliferation and apoptosis of gastric carcinoma cells. ......
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