俞丽芬,吴云林, 乔敏敏,钟捷, 涂水平,上海第二医科大学附属瑞金医院消化科 上海市 200025

    俞丽芬,女, 1970-10-28生,浙江省萧山市人,汉族, 2004年上海第二医科大学医学博士,主治医师, 讲师.

    上海市科学技术委员会基金资助课题,No.024119114

    项目负责人:俞丽芬,200025, 上海市瑞金二路197号,上海第二医科大学附属瑞金医院消化科. graceyu1028@sohu.com

    电话:021-64370045-665242 传真:021-64373909

    收稿日期:2004-03-05 接受日期:2004-03-16

    Effect ofStat3 antisense oligonucleotideon signal transductionpathway related to humanstomach adenocarcinoma MKN45cell line

    Li-FenYu, Yun-Lin Wu, Min-Min Qiao, Jie Zhong, Shui-Ping Tu

    Li-Fen Yu, Yun-Lin Wu, Min-Min Qiao, Jie Zhong, Shui-Ping Tu, Departmentof Gastroenterology, Ruijin Hospital of Shanghai Second MedicalUniversity, Shanghai 200025, China

    Supported by Shanghai Science and Technology Committee Fundation,No.024119114

    Correspondence to: Dr. Li-Fen Yu, Department of Gastroenterology,Ruijin Hospital of Shanghai Second Medical University, 197 Ruijiner Road,Shanghai 200025, China. graceyu1028@sohu.com

    Received: 2004-03-05 Accepted:2004-03-16

    AbstractAIM: To investigate the effect of antisense oligonucleotide (as-ODN)of Stat3 on the cell proliferation of human stomach adenocarcinoma cellline MKN45 and to determine the novel molecular target for treatment ofgastric cancer. ......