【摘要】 目的 探讨原发性胆囊癌的发病原因、诊断及治疗。方法 回顾分析原发性胆囊癌46例。结果 术后因肝功能衰竭死亡1例，有轻度胆漏2例，余均顺利出院。随访28例，Ⅰ期5例存活至今;Ⅱ期16例中10例存活，5例发生远处转移，1例因其它疾病死亡;Ⅲ期6例中2例至今存活，4例死亡;Ⅳ期1例已死亡。结论 胆囊结石是胆囊癌的高危因素。B超、CT及MRI检查是诊断本病的主要手段。根治性手术是胆囊癌的主要治疗方法。

    关键词 胆囊癌 病因 诊断 治疗

    Clinical analysis of46cases of primary gallblajjer cancinoma

    Zhu Jian，Xu Ji.

    Department of General surgery，Affiliated Xinhua Hospital，Shanghai Senond Medical University，Shanghai200092.

    【Abstract】 Objective To investigate the etiology，diagnosis and treatment ofprimary gallbladder cancer.Methˉods Retrospectively analyze46cases of gallbladder cancer.Results All cases are discharged uneventfully except that one died of postoperative liver failure and2cases of slight biliary leakage.There are28follow-up cases.5cases of stageⅠare alive so far.In16cases of stageⅡ，10are alive，5with distant metastasis and1died of other disease.In6case of stageⅢ，2are still alive and4died.One caseofstageⅣhasdied.Conclusion Gallbladder stone is a high risk factor for gallbladdercancer.Bscan ......