【摘要】 目的 观察左旋卡尼汀联合重组人促红细胞生成素(rhEPO)治疗肾性贫血的临床疗效。方法 54例维持血液透析的肾性贫血患者随机分为三组，A组18例，透析后静脉注射左旋卡尼汀1g;B组18例，采用rhEPO3000IU皮下注射2～3次/周治疗;C组，透析后静脉注射左旋卡尼汀1g，同时应用rhEPO3000IU皮下注射2～3次/周治疗。观察三组病人血浆白蛋白、血红蛋白、红细胞体积的变化。结果 随着治疗的进行，A组Alb显著升高，与B组比较，差异有显著性(P<0.05);C组血浆白蛋白、血红蛋白上升最明显，与A组、B组比较差异均有显著性(P<0.05)，C组rhEPO用量明显低于B组。结论 左旋卡尼汀可改善维持血液透析患者的状态，提高rhEPO的疗效，减少rhEPO的用量。

    关键词 肾性贫血 左旋卡尼汀 促红细胞生成素

    Effect of L-carnitine on patients with nephritic anemia treated with rhEPO

    Xu Yongzhi，Tang Deshen，Huang Zhiqing

    Department of Nephrology，Affiliated Hospital of Guangdong Medical College，Zhanjiang524001.

    【Abstract】 Objective To evaluate whether L-carnitine can further improve the effect of rhEPO on nephritic nemia.Methods 54patients with nephritic anemia were randomly divided into3groups.group A:18patients L-carnitine1.0g intravenously infused after every dialysis;group B:18patients accepted3000IU of rhEPO through subˉcutaneous injection2～3week;group C:L-carnitine and rhEPO are given together.The serum albumin ......