【摘要】 目的 讨论机械瓣膜置换术后妊娠妇女瓣膜栓塞的救治。方法 回顾性分析我院2例机械瓣膜置换术后妊娠妇女瓣膜血栓形成及重度梗阻，1例孕33周发现二尖瓣机械瓣膜重度梗阻，心功能Ⅳ级;1例为孕37周发生主动脉瓣机械瓣膜重度梗阻，二尖瓣机械膜血栓形成，心功能Ⅲ级。结果 在开胸直视下行剖宫产及子宫次全切除术，同时行机械瓣膜再次置换术，成功地挽救了母儿生命。结论 孕期合理应用抗凝药物，严密监测凝血指标及心脏瓣膜功能，尽可能避免瓣膜栓塞，一旦发生，在开胸直视下，同时行子宫下段剖宫产术、子宫次全切除术及心脏瓣膜置换术，不失为抢救母儿生命之急救方法。

    【Abstract】 Objective To discuss the treatment of valve embolism of pregnant women with the mechanical valve displacement.Methods Analyze two pregnant women with valve thromboembolism retrospectively.One case was33weeks gestation，whose mechanical mitral valve obstruct severely，cardiac function was gradeⅢ;another case was37weeks pregnant women，whose mechanical aortic valve obstruct severely and mitral valve thrombosis，cardiac function was gradeⅣ.Results Cesarean section combining with subtotal hysterectomy under monitoring heart，re-replacementmeˉchanical valve afterwards，which saved both maternal and newborn’s lives successfully.Conclusion Anticoagulating reaˉsonably during pregnancy，monitoring PT and APTT and checking mechanical valve in order to avoid valve embolism.Once occuring this complication ......