【摘要】 目的 探讨卵巢癌患者血清CA125与VEGF的相关性，为寻找卵巢癌早期诊断和疗效判断指标。方法 采用酶联免疫吸附双抗体夹心法检测对照组、良性卵巢肿瘤和卵巢癌患者血清CA125和游离VEGF的含量。结果恶性卵巢肿瘤组CA125、VEGF含量均显著高于良性肿瘤组(P<0.001);手术后恶性卵巢肿瘤组CA125、VEGF含量均降低，与手术前比较差异有非常显著性(P<0.001);卵巢癌患者CA125与VEGF之间呈显著相关性。结论 CA125、VEGF不仅可用于卵巢癌的早期诊断，而且可进行术后疗效的观察。

    关键词 卵巢肿瘤 CA125 VEGF

    Relationship between CA125and vascular endothelial growth factor of serum in patients with ovarian cancer

    Zhang Runling，Wang Hailin，Pan Yunyan

    Department of Laboratory，Second Affiliated Hospital，Lanzhou Medical College，Lanzhou，730030.

    【Abstract】 Objective To assess a correlation between CA125and human vascular endothelial growth factor(VEGF).Methods Using a sandwich enzyme-linked immunoabsorbent assay ......