【摘要】 目的 对比恩丹西酮、地塞米松静脉注射与氟哌利多用于PCEA中预防术后恶心呕吐的效果。方法 选择硬膜外麻醉下完成手术的患者120例。术毕均接受硬膜外吗啡镇痛，并随机分成4组。Ⅰ组(n=30):静脉不给止吐药;Ⅱ组(n=30):静注地塞米松10mg;Ⅲ组(n=30):静注恩丹西酮4mg;Ⅳ组(n=30):静注地塞米松10mg加恩丹西酮4mg，对术后恶心呕吐进行评估。结果 Ⅱ、Ⅲ、Ⅳ组恶心呕吐明显低于Ⅰ组(P<0.05)，Ⅳ组又明显低于Ⅱ、Ⅲ组(P<0.05)，而Ⅱ、Ⅲ组间差异无显著性(P>0.05)。结论 预防性静注恩丹西酮、地塞米松是一种减少PCEA引起恶心、呕吐的有效方法，氟哌利多、恩丹西酮、地塞米松三者合用对预防术后恶心呕吐具有协同作用。

    Huang Ni，Zheng Hailv

    Chaozhou Hospital，Chaozhou，Guangdong521011.

    【Abstract】 Objective To compare the effect of Ondansetran，Dexamethasone and Droperidol for prevention of postoperative nausea and vomiting(PONV)while to apply to PCEA respectively.Methods Patients of120cases acˉquired epidural anesthesia for surgeries were enrolled.All patients received epidural morphine for analgesia after the surgery and were divided into four groups randomly.TheⅠgroup(n=30):no antivomit drug ......