【摘要】 目的 探讨急性心血管疾病的发病、转归与血浆神经肽:神经肽Y(NPY)、神经降压素(NT)、β-内啡肽(β-EP)含量变化关系。方法 采用放射免疫测定法(RIA)分别检测33例急性心血管疾病(26例急性心肌梗死及各种急性心衰17例)发病后第1、3、7、14天血浆3种神经肽含量，并设相应对照组。结果 (1)急性心血管疾病的血浆β-EP、NPY、NT含量显著升高(P<0.01)。(2)发病时血浆神经肽水平最高，3天以后降低，至第14天接近正常。结论 血浆神经肽的水平不仅与急性心血管疾病的发生有密切关系，而且在病程观察

    中有重要价值。

    关键词 急性心血管病 βˉ内啡肽 神经肽Y 神经降压素

    Study of change of plasma neuropeptide levels in patients with acute cardiovascular disease

    He Ling，Xu Youfen，Lan Suixin，et al.

    Gongbei Hospital of Zhuhai，Guangdong519020.

    【Abstract】 Objective To explore the relationship between the dynamic changes of plasma neuropeptide(β-EP，NT，NPY)levels and the pathogenesis as well as clinical outcomes of acute cardiovascular diseases.Methods The concentrations of serum neuropeptide(β-EP，NT，NPY)were measured on the1st，3rd，7th，14th day after the onset of disease with RIA in33patients with acute cardiovascular(18cases of acute myocardial ......