【摘要】 目的 通过对乳牙急慢性根尖周炎感染根管的菌丛分析，揭示其可疑病原菌。方法 选择28颗患有根尖周炎的乳牙，其中急性15颗，慢性13颗。分别在微需氧(80%N 2 ，10%H 2 ，10%CO 2 )及厌氧条件(90%N 2 ，10%CO 2 )下进行患牙根管细菌分离和鉴定。结果 本实验共分离菌株199株，其中专性厌氧菌占69.34%，而兼性厌氧菌占26.63%，急性根尖周炎患牙根管内专性厌氧菌和兼性厌氧菌的检出率与慢性根尖周炎相比，差异均有显著性;产黑色素普氏菌、微小消化链球菌在急性根尖周炎组所占比例比慢性组高，差异有显著性(X 2 值分别为4.3919和13.9797，P<0.05)，而韦荣氏菌则相反，差异亦有显著性(X 2 值为5.6502，P<0.05)。其它各菌所占比例在两组间差异均无显著性。结论 产黑色素普氏菌、微小消化链球菌可能与急性根尖周炎的发生有关，而韦荣氏菌则与乳牙慢性根尖周炎的发生有一定的关联。

    关键词 乳牙 根尖周炎 根管 细菌

    Microbial flora of infected root canals of human deciduous teeth with periapical disease

    Wang Jun，Liu Zheng，Li Mingyu

    The9th Hospital Affiliated the Second Shanghai Medical University，Shanghai200011.

    【Abstract】 Objective The aim of the study was to investigate the suspicious pathogens of both acute and chronic periapical disease by analyzing the bacteria composition of infected root canal of human deciduous teeth.Methods Twenty-eight deciduous teeth including15with acute periapical disease and13with chronic periapical disease were selected for the study.The bacteria of the pulp were isolated and identified in80%N 2 ，10%H 2 ，10%CO 2 and in90%N 2 ......