【摘要】 目的 观察并评价经眼动脉插管灌注尿激酶溶栓治疗视网膜中央动脉阻塞的疗效。 方法 经股动脉插管，应用微导管技术将导管插入眼动脉局部注入尿激酶25～50万u进行溶栓治疗。 结果 8例中，4例术后视力明显提高。6个月后0.1～0.3者3例，>0.3者1例。其中1例从光感提高到0.25，1例从术前0.1提高到0.6，1例从术前指数提高到0.3。3例术后视力提高不理想。1例从术前指数下降至光感。2例术后并发脑梗死伴肢体瘫痪。 结论 早期应用超选眼动脉插管及溶栓可能比其他治疗方法更有效，但应注意术中术后并发症。

    关键词 视网膜中央动脉阻塞 溶栓治疗 尿激酶

    Superselective ophthalmic artery catheter thrombolysis in treatment of central retinal artery occlusion

    Lu Guohua，Li Rulong，Wang Xiaoyin，et al.

    Department of Ophthalmology，The2 nd People's Hospital of Changzhou Affiliated Hospital of Nanjing Medical University，Changzhou213003.

    【Abstract】 Objective To investigate the effect of superselective ophthalmic artery catheter thrombolysis for treatment of central retinal artery occlusion(CRAO).Methods 250000～500000u urokinase was directly infused via ophthalmic artery(OA)by catheterization after angiography into8eyes of8patients with CRAO.Results The visual acu-ity(VA)was significantly improved in4eyes.The VA of3eyes was0.1～0.3after6months follow-up.The other3eyes achieved improvement of VA non-significantly.The VA of1eye decreased from FC to LP.Conclusion Early di-agnosis and early superselective trans-micro catheter thrombolytic infusion would be more effective than raditional treat-ment. ......