【摘要】 目的 对2004年宝山区上报的266份药品不良反应(ADR)报告进行分析。 方法 对266份ADR报告进行统计和分析评价。 结果 新的、严重的ADR发生率为3.7%;药剂科和药品监管科上报ADR数量最多为58.6%;医生和药师分别上报了48.5%和48.1%，护士仅上报了3.4%;在引起ADR的药物中，抗微生物药物出现次数居首位占65.6%，这其中又以头孢菌素类抗生素出现次数最多;ADR引起的皮肤损害最多;ADR的上报数量逐季度快速增长;ADR报告表中缺项最多的是病历号/门诊号;在10份新的、严重的ADR报告中有4份上报时间超过半个月。 结论 应加强ADR知识的宣传，让医务工作者更加重视ADR监测，以达到安全用药目的。

    【关键词】 不良反应

    The analysis of adverse drug reaction in Baoshan district during2004

    Xia Yun，Shen Jinyan，Zhou Xuedong

    Baoshan Central Hospital，Shanghai201900.

    【Abstract】 Objective To analyse266ADR reports in Baoshan district during2004.Methods Statistical method was used to analyse and assess266ADR reports.Results The rate of new and severe ADR was3.7%.The highest reporting propotion which was reported by hospital pharmacy was58.6%.48.5%and48.1%.ADR reports were reported by doctors and pharmacists while only3.4%were reported by nurses.The leading drug that caused ADR was antibiotics(65.6%).Among all of these antibiotics ......