【摘要】 目的评价巴曲酶治疗突发性耳聋的效果和安全性。 方法对69例突发性耳聋的患者采用常规治疗(低分子右旋糖酐、ATP、辅酶A、地塞米松)。然后，采用随机对照双盲平行试验设计，将69例突发性耳聋的患者分成A、B两组。在常规治疗的基础上，A组34例患者用巴曲酶治疗，B组35例患者用血管扩张剂(红花)治疗。 结果 A组和B组的总有效率分别为85.3%(29/34)和62.9%(22/35)，两组比较差异有显著性(P<0.05)。 结论 巴曲酶治疗突发性耳聋疗效优于血管扩张剂，且安全，值得临床推广。

    关键词 突发性耳聋 巴曲酶 血管扩张剂

    Clinical analysis of batroxobin in treatment of sudden sensorineural hearing loss Zhu Xiaoping，Jiang Hui，Xu Lingen

    Department of Otorhinolaryngology，Jinshan Hospital of Fudan University，Shanghai200540.

    【Abstract】 Objective To assess the effects and safety of batroxobin on sudden sensorineural hearing loss(SSHL).Methods Firstly，69patients with SSHL were treated with routine treatment(low molecular weight dextran，ATP，C and dexamethasone).Secondly，in double-blind，parallel-group study69patients with SSHLwere randomly di-vided into two group.Thirty-four patients of group A were treated with batroxobin ......