【摘要】 目的 探讨不同疾病患者诱导痰细胞学的不同之处。 方法 对急性期哮喘患者29例(A组)、急性期慢性支气管炎患者30例(B组)、非气道疾病组14例(C组)进行气道反应性测定、痰液诱导及处理，分析3组患者痰液细胞构成的差异性，其结果数值输入SPSS10.0统计软件包进行统计。 结果 A组嗜酸性粒细胞百分率显著高于B组、C组(19.8%vs5.4%、1.3%);B组表现为中性粒细胞性炎症(66.4%vs45.3%、24.1%)，而C组以吞噬细胞(71.9%)为主。A组诱导痰中嗜酸粒细胞百分率与1秒用力肺活量(FEV1)表现出一定程度的负相关(相关系数r为0.470，P=0.024)。 结论 嗜酸性粒细胞对于哮喘气道炎症有较重要的作用，中性粒细胞在哮喘发病过程中可能起重要作用。

    【关键词】 哮喘 慢性支气管 气道炎症 炎症细胞

    The clinic value probe of induced sputum cells analysis to the asthma patients

    Yang Ruisheng，Xie Haiying.

    Songgang People's Hospital of Shenzhen Municipal，Shenzhen518105.

    【Abstract】 Objective To probe the differences of induced sputum cells of nifferen various diseases patients.Methods 29cases of acute asthmatic patients(A group)，30cases of chronic bronchitis patients in acute period(B group)and14cases of non-airway diseases patients(C group)were made through airway reaction test，sputum induc-ing an handling.Thedifferences of sputum cells structure of three groups patients were analyzed by statistic software SPSS10.0.Results The eosinophils cells in A group were high than those in B or C group(19.8%vs5.4%、1.3%);the neutrophil cells inflammation were mainly in B group(66.4%vs45.3%、24.1%) ......