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关键词：心肌梗死；心肌缺血预适应
【摘要】 目的 研究缺血预适应对心肌梗死范围及近期预后的影响。方法 将130例首次心肌梗死患者依据梗死前有无冠心病史、伴或不伴梗死前心绞痛发作分为A、B、C三组，统计各组出现的并发症和住院期死亡率；并通过心电图计分法和肌酸磷酸激酶(CK)峰值水平比较最初心肌梗死面积。结果 心梗中确存在缺血预适应，各组间统计学分析存在显著差异(P<0.05)。并且近、远期缺血预适应存在不同机制并有相加作用。结论 无论近期、远期心肌缺血预适应在心梗中对心肌均有保护作用，且两者有相加作用，其中近期缺血预适应在心梗中对心肌保护作用更显著，其机理有待进一步研究。
Effects of preconditioning on size and short-term prognosis of myocardial infarction
Zhuang Yihao, Wu Yeliang. Department of Cardiology, Shenzhen Red-Cross Hospital, Shenzhen 518029
【Abstract】 Objective To study effects of preconditioning on size of myocardial infarct and short-term prognosis.Method One hundred and thirty first AMI patients were divided into three groups according to with or without coronary heart disease and with or without angina pectoris before AMI complication, and death rate at admission were calculated and sizes of first myocardial infarct were compared with a QRS scoring system and peak level of CK among these groups. Result It was showed that there was actual preconditioning in AMI and there were signifcant differences among three groups. New and old preconditioning had different mechanisms with adding effect each other. Conclusion It is suggested that there is higher incidence of heart failure in AMI patients without new preconditioning, and therefore, its more death rate is not declined.
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