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关键词：牙周病；中西医结合
提要 目的 ：探讨中西医结合方法治疗牙周病的机理。方法 ：将292例牙周病患者随机分成两组，西医治疗组(对照组)164例，中西医结合治疗组(治疗组)128例，除西药治疗外，口服中药煎剂。结果 ：治疗组总有效率为92.96%，对照组75.60%，两组比较有显著性差异(P <0.01)。结论 ：中西医结合治疗牙周病是非常有效的方法，其作用机理可能有以下几个方面：①降低了血液粘度，增加细胞的韧性，使血流通畅。②通过增加前列环素I2 (PGI2 )和降低血栓素A2 (TXA2 )含量使血管扩张，降低血小板凝集性，以利于牙周组织的血液供应。③提高了超氧化物歧化酶(SOD)活力，减轻自由基对牙周组织的损伤。
Periodontal diseases treated byIntegrated traditional Chinese and western medicine: A clinical study of 128 cases
Sun Hong, et al
Abstract Objective : To explorethe mechanisms of periodontal diseases treated using integrated traditional Chinese andWestern medicine (TCM-WM). Methods : Two hundred and ninty-two patientswith periodontitis were divided into two groups 128 treated using the method of integratedTCM-WM and the other 164 treated using western medicine alone-as control. Results :The total effective rate of the treated group was 92.96%,and that of the control group was75.60%, with significant difference between two groups, P <0.01. Conclusion :The integrated method is very effective in treating sudden deafness. Its mechanism might①decrease the blood viscosity and the red blood cell tenacity, so that the blood streamis passing smoothly. ②decrease the plasma TXA2 level and increase the PGI2 level, keeping the blood supply to the periodontal tissue. ③increase the activity of SODand clear away the free radicals so as to reduce the damage to the periodontal tissue.
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