关键词：环丙沙星；甲硝唑；切口感染；脂肪厚度
提要 目的 ：研究环丙沙星与甲硝唑对手术切口封闭作用的差异和患者腹壁脂肪厚度对切口感染的影响。方法 ：386例急性化脓性阑尾炎穿孔、腹膜炎患者进行随机分组，分别用2%环丙沙星注射液及0.2%甲硝唑注射液进行切口封闭，用校正c2 检验两组P值，并按腹壁脂肪厚度分成两组，用校正c 2 统计量检验两组P 值。结果两个P 值分别为P <0.05和P <0.01。结论 ：用环丙沙星封闭急性化脓性阑尾炎穿孔、腹膜炎手术切口比甲硝唑更有效，并且证明切口感染与腹壁脂肪厚度有密切关系，腹壁脂肪越厚感染的概率越大。
Effects of ciprofloxacin andmetronidazole on incision sealing
Chen Guoming, et al
Abstract Objective :To study thedifference in the effects of ciprofloxacin and metronidazole on incision sealing and theinfluence of patient's belly fat thickness on incision infection. Methods :386 cases of acute purulent appendiceal perforation and peritonitis were grouped at randomand given 2% ciprofloxacin and 0.2% metronidazole injection liquids, respectively, withcorrection c 2 test for pvalue (P <0.05).They were divided into twogroups according to their belly fat thickness, with correction c 2 test forpvalue (P <0.01). Conclusion : It is better to seal incision ofacute purulent appendiceal perforation and peritonitis with ciprofloxacin than withMetronidazole. Further more,There is close relationship between incision infection andbelly fat thickness.
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