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编号:10681896
肝乐胶囊对实验性肝损伤的保护作用
http://www.100md.com 《中药新药与临床药理》 1999年第4期
@肝乐胶囊,药理学|肝炎,中药疗法,关键词:,ProtectiveEffectofGanleCapsuleonExperimentalHepaticInjuryinAnimalModels
     刘廷快 陈邦树 广西壮族自治区药品检验所,南宁530021 中药新药与临床药理 1999 0 10 4


    关键词:@肝乐胶囊/药理学;肝炎/中药疗法 期刊 zyxyylcyl 0 药效与毒理学研究 fur -->


    

摘要: 肝乐胶囊对大、小鼠四氯化碳及小鼠D-半乳糖胺(D-GalN)所致中毒性肝损伤造型有保护作用。实验表明,肝乐胶囊能显著抑制血清谷丙转氨酶(ALT)活性上升,同时提高大鼠血清超氧化物歧化酶(SOD)活性,肝组织病理学观察证实,肝乐胶囊能减轻肝细胞病理损害。

    中图分类号:285.5

    文献标识码:A 文章编号:1003-9783(1999)04-0213-03

Protective Effect of Ganle Capsule on Experi mental Hepatic Injury in Animal Models

LIU Tingkuai,CHEN Bangshu

    (Guangxi Zhuang Autonomous Region Institute for Drug Control,Nanning 530021)

Abstract: The protective effect of Ganle Cap sule(GC) on CCl4 - induced hepatic injury in mice and rats and D- Galactosalmine- induced hepatic injury in mice were studied.The result showed that GC could obviously inhibit the increase of glutamic pyruvic transamiase(ALT) activity and increase superoxide dismutase(SOD) activity in serum.The histopathological examination of hepatic tissue showed that GC could reduce the hepatocytic injury.

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