关键词:胎盘免疫调节因子;头颈部恶性肿瘤;自然杀伤细胞(NK);T细胞亚群
摘要 利用自研制的胎盘免疫调节因子(PIF)治疗头颈部恶性肿瘤62例。观察PIF对病人T细胞亚群和NK细胞活性的影响。结果显示,经PIF治疗后治疗组病人的外周血CD3 、CD4 、CD4 /CD8 比值及NK细胞活性均明显增高,CD8 降低。揭示PIF能提高头颈部恶性肿瘤病人的细胞免疫功能。
Effect of placental immunoregulating factor on cell immunological function of patients with head-neck malignant tumor
Zhang Litu,Liang Jiheng,Zhang Lisheng et al.Guangxi Cancer Institute,Nanning 530021
Abstract Placental immunoregulating factor(PIF) was used to treat 62 cases of patients with head-neck malignant tumor. The effect on T-cell subsets and NK cells activity of these patients was observed.The results showed that after PIF treatment,the NK cells activity,the CD+ 3 cells,the CD+ 4 cells and CD+ 3 /CD+ 4 ratio in the peripheral blood of treating group patients significantly increased.The result indicates that PIF can obviously promote the immunological function of patients with head-neck malignant tumor.
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