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心肌细胞外基质的改变与心力衰弱
http://www.100md.com 《基础医学与临床》 2000年第3期
心肌细胞外基质的改变与心力衰弱
心肌细胞外基质的改变与心力衰弱

     田斌 基础医学与临床 2000 0 20 3


    关键词: 期刊 jcyxylc 0 心肌肥大和心力衰竭的细胞内信号转导机制专题 fur -->


    

中图分类号:R541 文献标识码:A 文章编号:1001-6352(2000)03-0022-06

Abstract:Cardiacextracellular matrix(ECM) consists of several groups of extracellularmacromolecules.In adult myocardium,the major components of ECM include collagen subtypes,fibronectin,laminin,metalloproteases(MMP),and tissue inhibitors of metalloproteases(TIMP).As a major component,cardiaccollagen provides alignment to myocardial cells and serves as the skeleton of cardiaccollagen network(CNW),Which maintains the ventricular chambers in normal structuralarchitecture and function. Chronic congestive heart failure(CHF) ......


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