Coinhibitory effect of recombinant tumor necrosis factor α and mutant interleukin-2 on H7402*
tumornecrosisfactor,pharmacology|interleukin,pharmacology|liverneoplasms,drugtherapy|drugsynergism,Coinhibitoryeffectofrecombinanttumornecrosisfactorαandmutantinterleukin-2onH7402*,关键词：
关键词：tumor necrosis factor/pharmacology; interleukin/pharmacology; liver neoplasms/drug therapy; drug synergism
Abstract
AIM Toobserve the effect of recombinant tumor necrosis factor α (rHTNFα) and mutantinterleukin-2 (IL-2) on the hepatocarcinoma cell line in vitro.
METHODS The hepatocarcinoma cellline (H7402) was used as a cell culture system in vitro. H7402 was cultured with differentconcentrations of rHTNFα and/or mutatant IL-2. Thecytotoxity was measured by short-term MTT method.
RESULTS The inhibitory effect onH7402 became stronger with the increase of the concentration of rHTNFα (r=0.909 ......
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