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系统性红斑狼疮的消化系统临床表现157例分析
http://www.100md.com 《中华消化杂志》 1999年第1期
系统性红斑狼疮|消化系统|结核,关键词:
     张烜 曾学军 董怡 陆星华 李明佳 100730 中国医学科学院 中国协和医科大学 北京协和医院 中华消化杂志 1999 0 19 1


    关键词:系统性红斑狼疮;消化系统;结核 期刊 zhxhzz 0 论著 fur -->


    

【摘要】 目的 探讨系统性红斑狼疮(SLE)消化系统累及的发生率及临床表现。方法 对1990年1月~1997年7月北京协和医院诊断明确资料完整的277例SLE住院病例进行分析。结果 其中有消化系统症状体征或实验室异常者多达157例,占56.7%。98例(35.4%)无明确酒精、药物、感染病因,且与SLE活动性有关(P<0.01)。值得注意的是:44例以胃肠病变为首发或主要表现的SLE病例中,误诊39例(88.6%),最易误诊为感染性疾病,尤其是结核,其次为其它自身免疫性疾病及肿瘤。结论 SLE消化系统表现的发生率高,容易误诊,临床应引起重视。

D igestive system involvement in systemic lupus erythematosus

    
ZHANG Xuan, ZENG Xuejun, DONG Yi, et al.

    
Pecking Union Medical College Hospital, Beijing, 100730

Abstract Objectives To investigate the clinical manifestations of digestive system involvement in systemic lupus erythematosus (SLE). Methods Two hundred and seventy-seven inpatients concordant with the diagnostic criteria of SLE in this hospital since 1990 were analyzed retrospectively. Results Among these, 157(56.7%) had symptoms, signs and laboratory abnormalities of digestive system. involvement. 98(35.4%) could only be ascribed to SLE istelf, and were concordant with lupus activity(P < 0.01). It was noteworthy that in 44 cases gastrointestinal involvements were the presenting manifestations of SLE, of which 39 were misdiagnosed(88.6%) as infectious disease, in particular, tuberculosis, other autoimmune disease or tumor. Conclusions Digestive system involvements occur with high frequency in SLE and are easily misdiagnosed which should not be overlooked.

    
Key words Systemic lupus erythematosus Digestive system Tuberculosis

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