摘要 为探讨腹腔镜手术后血栓栓塞性并发症发生机制，观察一组腹腔镜胆囊切除术(LC)患者手术前后血液凝固性改变的情况，并将开腹胆囊切除组资料作为对照。结果表明LC术后平均血小板体积、纤维蛋白原水平及P-选择素、凝血酶敏感蛋白表达阳性血小板比率明显增高。对照组术后凝血酶原时间、激活的部分凝血活酶时间均显著延长，LC组无明显改变。表明腹腔镜手术后患者血液处于明显高凝状态。提示对有血栓形成倾向的患者应采取抗凝措施，以预防血栓栓塞性并发症。

    HYPERCOAGULABILITY FOLLOWING LAPAROSCOPIC CHOLECYSTECTOMY

    Zhu Jiangfan，Shan Licheng，Sun Xiaoming，et al.Department of General Surgery，

    General Hospital of Jinan Unit，PLA，Jinan 250031

    Abstract This article reports the study of blood coagulability following

    laparoscopic clolecystectomy (LC) for gallbladder stones.Patients (n＝20) subjected to LC were compared with those who had open cholecystectomy (OC ......