关键词:良性前列腺增生症;流行病学
【摘要】 目的 了解常州及武进地区前列腺增生症(BPH)的发病情况。 方法 调查该地区40岁以上男性2 433人的国际前列腺症状评分(IPSS)、生活质量评分(L)、最大尿流率(Qmax)、前列腺体积(V)及剩余尿(R)等情况,其中城镇职工1089人,农民1 344人,测量118人血睾酮(T)、双氢睾酮(DHT),询问1957人性活动情况。 结果 BPH发病率占总调查人数(2433)的25.7%,城镇职工30.4%,农民21.9%;BPH组血DHT明显高于正常组(P<0.01);初次性交时间早及失去性功能年龄大者BPH发病率高(P<0.01)。 结论 城镇职工BPH的发病率高于农民,血DHT升高与BPH的发生有关,初次性交时间早(<25岁)及性功能维持年限长与BPH有关。
An epidemiological studyof BPH in Chinese
MO Naixin, LU Zhong, WU Lianfen,etal
Department of Urology,Wujin People's Hospital, Changzhou, Jiangsu 213003
【 Abstract】 Objective To investigate theincidence of benign prostatic hyperplasia (BPH) in Changzhou and Wujin districts. Methods An investigation of theincidence of BPH in 2 433 male inhabitants over 40 years of age,1 089 urban and 1 344rural,has been carried out including I-PSS,life quality (L),Qmax,volume of prostate (V)and residual urine(R) studies.Plasma testosterone and dihydrotestosterone were assayed inall the subjects investigated.Sexual behavior was recorded in 1957. Results The incidence of BPH was 25.7%,being 30.4% in the urbanhabitants and 21.9% in the rural.A significant increase of dihydrotestosterone was notedin BPH subjects.The earlier the age of the occurrence of first sexual intercourse and thelater the loose of sexual activity in the aged the higher would be the incidence of BPH (P< 0.01). Conclusions The increase of BPH has been higher in the urbaninhabitants.The increase of plasma dihydrotestosterone might play a role in thedevelopment of BPH.The earlier the age of the occurrecnce of first sexual intercourse andthe later the loose of sexual activity in the elders were associated with a higherincidence of BPH.
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